Relevant Publications

2023
Self-Immolative Nanobody-Cysteine Residue Modification for Controlled Immunodrug Delivery
Maximilian Scherger, Yannick A. Pilger, Judith Stickdorn, Patric Komforth, Sascha Scshmitt, Sana Arnouk, Els Lebegge, Kaloian Koynov, Hans-Joachim Räder, Jo A. Van Ginderachter, Lutz Nuhn
Advanced Therapeutics June 2023, DOI:10.1021/ acsbiomaterials.2c01106.
Impact Factor: 5 more
MUC1 Glycopeptide Vaccine Modified with a GalNAc Glycocluster Targets the Macrophage Galactose C-type Lectin on Dendritic Cells to Elicit an Improved Humoral Response
A. Gabba, R. Attariya, S. Behren, C. Pett, J.C. van der Horst, H. Yurugi, J. Yu, M. Urschbach, J. Sabin, G. Birrane, E. Schmitt, S.J. van Vliet, P. Besenius, U. Westerlind, P.V. Murphy, J.
Am. Chem. Soc. June 2023, DOI: 10.1021/jacs.2c12843
Impact Factor: 16.4 more
Efficient Self-Immolative RAFT End Group Modification for Macromolecular Immunodrug Delivery
Maximilian Scherger, Yannick A. Pilger, Judith Stickdorn, Patric Komforth, Sascha Schmitt, Kaloian Koynov, Hans-Joachim Räder, Lutz Nuhn
Biomacromolecules April 2023, 24, 2380-2391
Impact Factor: 6 more
Reversible Polymer–Protein Functionalization by Stepwise Introduction of Amine-Reactive, Reductive-Responsive Self-Immolative End Groups onto RAFT-Derived Polymers
Maximilian Scherger, Yannick A. Pilger, Patric Komforth, Hans-Joachim Räder, Lutz Nuhn
ACS Biomaterials Science & Engineering Jan 2023
Impact Factor: 5.4 more
Quality by Design (QbD) Approach for a Nanoparticulate Imiquimod Formulation as an Investigational Medicinal Product
Pielenhofer, J., S. L. Meiser, K. Gogoll, A.-M. Ciciliani, M. Denny, M. Klak, B. M. Lang, P. Staubach, S. Grabbe, H. Schild, M. P. Radsak, H. Spahn-Langguth, P. Langguth
Pharmaceutics Feb 2023;5:514. doi: 10.3390/pharmaceutics15020514
Impact Factor: 6.5 more
Antibacterial Nanostructured Surfaces Modulate Protein Adsorption, Inflammatory Responses, and Fibrous Capsule Formation
Visalakshan RM, Bright R, Burzava ALS, Barker AJ, Simon J, Ninan N, Palms D, Wood J, Martínez-Negro M, Morsbach S, Mailänder V, Anderson PH, Brown T, Barker D, Landfester K, Vasilev K
ACS Appl Mater Interfaces. 2023 Jan 11;15(1):220-235. doi: 10.1021/acsami.2c13415.
Impact Factor: 10.4 more
A new methodology combining QCM-D and proteomic profiling enables characterization of protein adsorption on 2D surfaces
Martínez-Negro M, Oberländer J, Simon J, Mailänder V, Morsbach S, Landfester K
J Colloid Interface Sci. 2023 Jan 15;630(Pt A):965-972. doi: 10.1016/j.jcis.2022.10.090.
Impact Factor: 9.9 more
Systematic modulation of the lipid composition enables the tuning of liposome cellular uptake
Mateos-Maroto A, Gai M, Brückner M, da Costa Marques R, Harley I, Simon J, Mailänder V, Morsbach S, Landfester K.
ACS Appl Mater Interfaces. 2023 Jan 18;15(2):2891-2900. doi: 10.1021/acsami.2c17607. Epub 2023 Jan 3.
Impact Factor: 9.2
  more
R Li, J Heuer, T Kuckhoff, K Landfester, C Ferguson
Angew Chem Int Ed Engl. 2023 Feb 7. doi: 10.1002/anie.202217652.
Impact Factor: 16.8 more
S Han, R da Costa Marques, J Simon, A Kaltbeitzel, K Koynov, Katharina Landfester, V Mailänder, I Lieberwirth
Nature Comm. volume 14, Article number: 295 (2023)
Impact Factor: 17.7 more
2022
A Modular Platform of Carbohydrates-Modified Supramolecular Polymers Based on Dendritic Peptide Scaffolds
L. Li, L. Wu, M. Urschbach, D. Straßburger, X. Liu, P. Besenius, G. Chen,
ACS Polym. Au 2022, 2, 478–485. DOI: 10.1021/acspolymersau.2c00032.
  more
Sohl, J., A.-K. Hartmann, J. Hahlbrock, J. Bartneck, M. Stassen, M. Klein, M. Bros, S. Grabbe, F. Marini, K. Woods, B. Guezguez, M. Mack, H. Schild, S. Muth, F. Melchior, H. C. Probst, P. Langguth, M. P. Radsak
npj Vaccines 2022;7:112. doi: 10.1038/s41541-022-00530-9
Impact Factor: 9.4
  more
Poly(ethylene glycol)-Based Surfactant Reduces the Conformational Change of Adsorbed Proteins on Nanoparticles
M. Martínez-Negro, D. Russo, S. Prévost, J. Teixeira, S. Morsbach, K. Landfester
Biomacromolecules 2022, 23, 4282–4288
Impact Factor: 7.0 more
M. Brückner, M. Fichter, R. da Costa Marques, K. Landfester, V. Mailänder
Pharmaceutics 2022, 14(8), 1614
Impact Factor: 6.1 more
Proteomics reveals differential adsorption of angiogenic platelet lysate proteins on calcium phosphate bone substitute materials
R. da Costa Marques, J. Simon, C. d’Arros, K. Landfester, K. Jurk, V. Mailänder
Regenerative Biomaterials 2022, 9, rbac044
Impact Factor: 5.2 more
In Situ Assembly of Platinum(II)-Metallopeptide Nanostructures Disrupts Energy Homeostasis and Cellular Metabolism
Z. Zhou, K. Maxeiner, P. Moscariello, S. Xiang, Y. Wu, Y. Ren, C.J. Whitfield, L. Xu, A. Kaltbeitzel, S. Han, D. Mücke, H. Qi, M. Wagner, U. Kaiser, K. Landfester, I. Lieberwirth, D.Y.W. Ng, T. Weil
J. Am. Chem. Soc. 2022, 144, 12219−12228
Impact Factor: 16.4 more
Multicomponent encapsulation into fully degradable protein nanocarriers via interfacial azide–alkyne click reaction in miniemulsion allows the co-delivery of immunotherapeutics
N. Hüppe, J. Schunke, M. Fichter, V. Mailänder, F.R. Wurm, K. Landfester
Nanoscale Horiz. 2022, 7, 908–915
Impact Factor: 11.0 more
Dual-Targeted Nanoreactors and Prodrugs: Hydrogen Peroxide Triggers Oxidative Damage and Prodrug Activation for Synergistic Elimination of Cancer Cells
S.-M. Jo, H.S. Kim, M. Won, C. Champanhac, J.S. Kim, F.R. Wurm, K. Landfester
Adv. Funct. Mater. 2022, 32, 2200791
Impact Factor: 19.9 more
Nanocarriers with Multiple Cargo Load - A Comprehensive Preparation Guideline Using Orthogonal Strategies
N. Hueppe, F.R. Wurm, K. Landfester
Macromol. Rapid Commun. 2022, 2200611
Impact Factor: 5.0 more
Polymer nano-systems for the encapsulation and delivery of active biomacromolecular therapeutic agents
M. Machtakova, H. Therien-Aubin, K. Landfester
Chem. Soc. Rev. 2022, 51, 128-152
Impact Factor: 60.1 more
Achieving dendritic cell subset-specific targeting in vivo by site-directed conjugation of targeting antibodies to nanocarriers
J. Simon, M. Fichter, G. Kuhn, M. Brückner, C. Kappel, J. Schunke, T. Klaus, S. Grabbe, K. Landfester, V. Mailänder
NanoToday 2022, 43, 101375
Impact Factor: 20.7 more
S. Wirsching, M. Machtakova, F. Borgans, L. Pretsch, M. Fichter, M.L. Cacicedo, H. Thérien-Aubin, K. Landfester, S. Gehring
Frontiers in Pedeatrics, 2022, 10.3389/fped.2022.966113
Impact Factor: 3.4 more
Anne Huppertsberg, Christian Leps, Irina Alberg, Christine Rosenauer, Svenja Morsbach, Katharina Landfester, Stefan Tenzer, Rudolf Zentel, Lutz Nuhn – Macromolecular Rapid Communications 2022, 43, 202200318.
Impact Factor: 5.0 more
Kaps L, Huppertsberg A, Choteschovsky N, Klefenz A, Durak F, Schrörs B, Diken M, Eichler E, Rosigkeit S, Schmitt S, Leps C, Schulze A, Foerster F, Bockamp E, De Geest BG, Koynov K, Räder HJ, Tenzer S, Marini F, Schuppan D, Nuhn L
Proc Natl Acad Sci U S A. 2022 Mar 22;119(12)
Impact Factor: 12.8 more
Systemically Administered TLR7/8 Agonist and Antigen-Conjugated Nanogels Govern Immune Responses against Tumors
Stickdorn J, Stein L, Arnold-Schild D, Hahlbrock J, Medina-Montano C, Bartneck J, Ziß T, Montermann E, Kappel C, Hobernik D, Haist M, Yurugi H, Raabe M, Best A, Rajalingam K, Radsak MP, David SA, Koynov K, Bros M, Grabbe S, Schild H, Nuhn L. ACS Nano. 2022 Mar 22;16(3)
Impact Factor: 18.0 more
Müller P, Maus H, Hammerschmidt SJ, Knaff PM, Mailänder V, Schirmeister T, Kersten C. Curr Med Chem. 2022;29(4)
Impact Factor: 4.7 more
Temperature-Responsive Nanoparticles Enable Specific Binding of Apolipoproteins from Human Plasma
Prawatborisut M, Oberländer J, Jiang S, Graf R, Avlasevich Y, Morsbach S, Crespy D, Mailänder V, Landfester K.
Small. 2022 Jan;18(3)
Impact Factor: 15.2 more
Antibody-Functionalized Carnauba Wax Nanoparticles to Target Breast Cancer Cells
Iyisan B, Simon J, Avlasevich Y, Baluschev S, Mailaender V, Landfester K.
ACS Appl Bio Mater. 2022 Feb 21;5(2)
Impact Factor: 4.0 more
Nanocarriers Made of Proteins: Intracellular Visualization of a Smart Biodegradable Drug Delivery System
Frey ML, Han S, Halim H, Kaltbeitzel A, Riedinger A, Landfester K, Lieberwirth I
Small. 2022 Apr;18(15)
Impact Factor: 15.2 more
Shining Light on Polymeric Drug Nanocarriers with Fluorescence Correlation Spectroscopy 
Schmitt S, Nuhn L, Barz M, Butt HJ, Koynov K. Macromol Rapid Commun. 2022 Feb 17
Impact Factor: 5.0 more
Fluorescence Correlation Spectroscopy Monitors the Fate of Degradable Nanocarriers in the Blood Stream
Schmitt S, Huppertsberg A, Klefenz A, Kaps L, Mailänder V, Schuppan D, Butt HJ, Nuhn L, Koynov K. Fluorescence Correlation Spectroscopy Monitors the Fate of Degradable Nanocarriers in the Blood Stream. Biomacromolecules. 2022 Mar 14;23(3)
Impact Factor: 7.0 more
2021
Dual Stimuli-Responsive Dynamic Covalent Peptide Tags: Toward Sequence-Controlled Release in Tumor-like Microenvironments
Zegota MM, Müller MA, Lantzberg B, Kizilsavas G, Coelho JAS, Moscariello P, Martínez-Negro M, Morsbach S, Gois PMP, Wagner M, Ng DYW, Kuan SL and Weil T more
Capelôa L, Yazdi M, Zhang H, Chen X, Nie Y, Wagner E, Lächelt U and Barz M
Macromol Rapid Commun. 2021 Dec 30
Impact Factor: 5.0 more
Alpha-single chains of collagen type VI inhibit the fibrogenic effects of triple helical collagen VI in hepatic stellate cells
Freise C, Lee H, Chronowski C, Chan D, Cziomer J, Rühl M, Dagdelen T, Lösekann M, Erben U, Catic A, Tegge W, Schuppan D, Somasundaram R, Sahin E
PLoS One 2021 Sep 2
Impact Factor: 3.8 more
A structurally engineered fatty acid, icosabutate, suppresses liver inflammation and fibrosis in NASH
Fraser DA, Wang X, Lund J, Nikolić N, Iruarrizaga-Lejarreta M, Skjaeret T, Alonso C, Kastelein JJP, Rustan AC, Kim YO and Schuppan D
J Hepatol. 2021 Dec 13
Impact Factor: 30.1 more
pH-Dependent Behavior of Ionizable Cationic Lipids in mRNA-Carrying Lipoplexes Investigated by Molecular Dynamics Simulations

pH-Dependent Behavior of Ionizable Cationic Lipids in mRNA-Carrying Lipoplexes Investigated by Molecular Dynamics Simulations

Settanni G, Brill W, Haas H and Schmid F
Macromol Rapid Commun. 2021 Dec 7
Impact Factor: 5.0
Raabe M, Heck AJ, Führer S, Schauenburg D, Pieszka M, Wang T, Zegota MM, Nuhn L, Ng DYW, Kuan SL and Weil T
Macromol Biosci 2021 Nov 17
Impact Factor: 5.9 more
Density of Conjugated Antibody Determines the Extent of Fc Receptor Dependent Capture of Nanoparticles by Liver Sinusoidal Endothelial Cells
Kappel C, Seidl C, Medina-Montano C, Schinnerer M, Alberg I, Leps C, Sohl J, Hartmann AK, Fichter M, Kuske M, Schunke J, Kuhn G, Tubbe I, Paßlick D, Hobernik D, Bent R, Haas K, Montermann E, Walzer K, Diken M, Schmidt M, Zentel R, Nuhn L, Schild H, Tenzer S, Mailänder V, Barz M, Bros M and Grabbe S
ACS Nano 2021 Sep 28
Impact Factor: 18.0 more
Novel Biodegradable Composite of Calcium Phosphate Cement and the Collagen I Mimetic P-15 for Pedicle Screw Augmentation in Osteoporotic Bone 
Krenzlin H, Foelger A, Mailänder V, Blase C, Brockmann M, Düber C, Ringel F and Keric N
Biomedicines 2021 Oct 4
Impact Factor: 4.8 more
Transparent polycarbonate coated with CeO2 nanozymes repel Pseudomonas aeruginosa PA14 biofilms 
Jegel O, Pfitzner F, Gazanis A, Oberländer J, Pütz E, Lange M, von der Au M, Meermann B, Mailänder V, Klasen A, Heermann R and Tremel W
Nanoscale 2021 Dec 23
Impact Factor: 8.3 more
Temperature-Responsive Nanoparticles Enable Specific Binding of Apolipoproteins from Human Plasma
Prawatborisut M, Oberländer J, Jiang S, Graf R, Avlasevich Y, Morsbach S, Crespy D, Mailänder V and Landfester K
Small 2021 Nov 10
Impact Factor: 15.2 more
M. Prawatborisut, S. Jiang, J. Oberländer, V. Mailänder, D. Crespy and K. Landfester
Adv. Funct. Mater 2021
Impact Factor: 19.9 more
Controlling the semi-permeability of protein nanocapsules influences the cellular response to macromolecular payloads
Machtakova M, Wirsching S, Gehring S, Landfester K and Thérien-Aubin H
J Mater Chem B 2021 Oct 20
Impact Factor: 7.6 more
Johann K, Bohn T, Shahneh F, Luther N, Birke A, Jaurich H, Helm M, Klein M, Raker VK, Bopp T, Barz M and Becker C
Nat Commun. 2021 Oct 13;12(1):5981
Impact Factor: 17.7 more
N. Ritt, A. Ayaou and R. Zentel
Macromol. Chem. Phys. 2100122, online (2021); DOI: 10.1002/macp.202100122
Impact Factor: 3.0 more
Polymer cyclization for the emergence of hierarchical nanostructures
Chen, C., Singh, M. K.; Wunderlich, K.; Harvey, S.; Whitfield, C., Zhou, Z.; Wagner, M.; Landfester, K.; Lieberwirth, I.; Fytas, G.; Kremer, K., Mukherji, D.; Ng, D. Y. W., Weil, T.
Nature Communications 2021 doi.org/10.1038/s41467-021-24222-5
Impact Factor: 17.7 more
Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-Like Receptor 7/8 Agonistic Immune Modulators
A. Huppertsberg, L. Kaps, Z. Zhong, S. Schmitt, J. Stickdorn, K. Deswarte, F. Combes, C. Czysch, J. De Vrieze, S. Kasmi, N. Choteschovsky, A. Klefenz, C. Medina-Montano, P. Winterwerber, C. Chen, M. Bros, S. Lienenklaus, N. N. Sanders, K. Koynov, D. Schuppan, B. N. Lambrecht, S. David, B. G. De Geest, L. Nuhn
Journal of the American Chemical Society 2021, DOI: 10.1021/jacs.1c03772 
Impact Factor: 16.4 more
Contactless Nanoparticle-Based Guiding of Cells by Controllable Magnetic Fields
Blümler, P.; Friedrich, R. P.; Pereira, J.; Baun, O.; Alexiou, C.; Mailänder, V
Nanotechnol Sci Appl. 2021, 14:91-100
Impact Factor: 3.8 more
Self-sustaining enzyme nanocapsules perform on-site chemical reactions
Machtakova, S. Han, Y. Yangazoglu, I. Lieberwirth, H. Therien-Aubin, K. Landfester
Nanoscale 2021, 13, 4051-4059
Impact Factor: 8.3 more
Enzyme-Loaded Nanoreactors Enable the Continuous Regeneration of Nicotinamide Adenine Dinucleotide in Artificial Metabolisms
S.M. Jo, F.R. Wurm, K. Landfester
Angew. Chem. Intern. Ed. 2021, 60, 7728-7734
Impact Factor: 16.8 more
Contactless Nanoparticle-Based Guiding of Cells by Controllable Magnetic Fields
Blumler, P., Friedrich, R.P., Pereira, J., Baun, O., Alexiou, C., and Mailander, V.
Nanotechnol Sci Appl, 2021. 14: p. 91-100.
Impact Factor: 6.29 more
The conjugation strategy affects antibody orientation and targeting properties of nanocarriers
Bruckner, M., Simon, J., Landfester, K., and Mailander, V.
Nanoscale, 2021. 13(21): p. 9816-9824.
Impact Factor: 7.79 more
Encapsulation of polyprodrugs enables an efficient and controlled release of dexamethasone
Li, M., Jiang, S., Haller, A., Wirsching, S., Fichter, M., Simon, J., Wagner, M., Mailander, V., Gehring, S., Crespy, D., and Landfester, K.
Nanoscale Horizons,  2021. 6(10): p. 791-800.
Impact Factor: 9.94 more
Brush Conformation of Polyethylene Glycol Determines the Stealth Effect of Nanocarriers in the Low Protein Adsorption Regime
Li, M., J. Simon, D. Paßlick, M.L. Frey, M. Wagner, V. Mailänder, D. Crespy, and K. Landfester
Nano Letters, 2021. 21(4): p.1591-1598.
Impact Factor: 11.238 more
Heparin modulates the cellular uptake of
nanomedicines
Champanhac, C., H. Haas, K. Landfester, and V. Mailänder
Biomaterials Science, 2021. 9(4): p.1227-1231.
Impact Factor: 6.183
more
Unraveling the In Vivo Protein Corona
Simon, J., G. Kuhn, M. Fichter, S. Gehring, K. Landfester, and V. Mailander
Cells, 2021. 10(1).
Impact Factor: 4.366 more
2020
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma
Sahin, U., P. Oehm, E. Derhovanessian, R.A. Jabulowsky, M. Vormehr, M. Gold, D. Maurus, D. Schwarck-Kokarakis, A.N. Kuhn, T. Omokoko, L.M. Kranz, M. Diken, S. Kreiter, H. Haas, S. Attig, R. Rae, K. Cuk, A. Kemmer-Bruck, A. Breitkreuz, C. Tolliver, J. Caspar, J. Quinkhardt, L. Hebich, M. Stein, A. Hohberger, I. Vogler, I. Liebig, S. Renken, J. Sikorski, M. Leierer, V. Muller, H. Mitzel-Rink, M. Miederer, C. Huber, S. Grabbe, J. Utikal, A. Pinter, R. Kaufmann, J.C. Hassel, C. Loquai, and O. Tureci
Nature, 2020. 585(7823): p. 107-112.
Impact Facture: 42.778
In Vivo siRNA Delivery to Immunosuppressive Liver Macrophages by α-Mannosyl-Functionalized Cationic Nanohydrogel Particles
Kaps, L., N. Leber, A. Klefenz, N. Choteschovsky, R. Zentel, L. Nuhn, and D. Schuppan
Cells, 2020. 9(8).
Impact Factor: 4.366 more
Synergistic Anticancer Therapy by Ovalbumin Encapsulation‐Enabled Tandem Reactive Oxygen Species Generation
Jiang, S., M. Xiao, W. Sun, D. Crespy, V. Mailander, X. Peng, J. Fan, and K. Landfester
Angew Chem Int Ed Engl, 2020. 59(45): p. 20008-20016.
Impact Factor: 12.959 more
Controlling protein interactions in blood for effective liver immunosuppressive therapy by silica nanocapsules
Jiang, S., D. Prozeller, J. Pereira, J. Simon, S. Han, S. Wirsching, M. Fichter, M. Mottola, I. Lieberwirth, S. Morsbach, V. Mailander, S. Gehring, D. Crespy, and K. Landfester
Nanoscale, 2020. 12(4): p. 2626-2637.
Impact Factor: 6.895 more
Polymeric Nanoparticles with Neglectable Protein Corona
Alberg, I., S. Kramer, M. Schinnerer, Q. Hu, C. Seidl, C. Leps, N. Drude, D. Mockel, C. Rijcken, T. Lammers, M. Diken, M. Maskos, S. Morsbach, K. Landfester, S. Tenzer, M. Barz, and R. Zentel
Small, 2020. 16(18): p. e1907574.
Impact Factor: 11.459 more
Precision Anisotropic Brush Polymers by Sequence Controlled Chemistry
Chen, C., K. Wunderlich, D. Mukherji, K. Koynov, A.J. Heck, M. Raabe, M. Barz, G. Fytas, K. Kremer, D.Y.W. Ng, and T. Weil
J Am Chem Soc, 2020. 142(3): p. 1332-1340.
Impact Factor: 14.612
Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle–Cell Interactions
Dal, N.K., A. Kocere, J. Wohlmann, S. Van Herck, T.A. Bauer, J. Resseguier, S. Bagherifam, H. Hyldmo, M. Barz, B.G. De Geest, and F. Fenaroli
Small, 2020. 16(5): p. e1906719.
Impact Factor: 11.459
Integration of Indocyanine Green Analogs as Near‐Infrared Fluorescent Carrier for Precise Imaging‐Guided Gene Delivery
Liang, H., X. Chen, R. Jin, B. Ke, M. Barz, H. Ai, and Y. Nie
Small, 2020. 16(10): p. e1906538.
Impact Factor: 11.459
DNA–Polymer Nanostructures by RAFT Polymerization and Polymerization‐Induced Self‐Assembly
Luckerath, T., K. Koynov, S. Loescher, C.J. Whitfield, L. Nuhn, A. Walther, C. Barner-Kowollik, D.Y.W. Ng, and T. Weil
Angew Chem Int Ed Engl, 2020. 59(36): p. 15474-15479.
Impact Factor: 12.959
The Influence of Nanoparticle Shape on Protein Corona Formation
Madathiparambil Visalakshan, R., L.E. Gonzalez Garcia, M.R. Benzigar, A. Ghazaryan, J. Simon, A. Mierczynska-Vasilev, T.D. Michl, A. Vinu, V. Mailander, S. Morsbach, K. Landfester, and K. Vasilev
Small, 2020. 16(25): p. e2000285.
Impact Factor: 11.459
Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging
Steen, E.J.L., J.T. Jorgensen, K. Johann, K. Norregaard, B. Sohr, D. Svatunek, A. Birke, V. Shalgunov, P.E. Edem, R. Rossin, C. Seidl, F. Schmid, M.S. Robillard, J.L. Kristensen, H. Mikula, M. Barz, A. Kjaer, and M.M. Herth
ACS Nano, 2020. 14(1): p. 568-584.
Impact Factor: 14.588
Amphiphilic Polyphenylene Dendron Conjugates for Surface Remodeling of Adenovirus 5
Wagner, J., L. Li, J. Simon, L. Krutzke, K. Landfester, V. Mailander, K. Mullen, D.Y.W. Ng, Y. Wu, and T. Weil
Angew Chem Int Ed Engl, 2020. 59(14): p. 5712-5720.
Impact Factor: 12.959
Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles
Wang, B., S. Van Herck, Y. Chen, X. Bai, Z. Zhong, K. Deswarte, B.N. Lambrecht, N.N. Sanders, S. Lienenklaus, H.W. Scheeren, S.A. David, F. Kiessling, T. Lammers, B.G. De Geest, and Y. Shi
J Am Chem Soc, 2020. 142(28): p. 12133-12139.
Impact Factor: 14.612
2019
Ligand density on nanoparticles: A parameter with critical impact on nanomedicine
Alkilany, A.M., L. Zhu, H. Weller, A. Mews, W.J. Parak, M. Barz, and N. Feliu
Adv Drug Deliv Rev, 2019. 143: p. 22-36.
Impact Factor: 13.30
Poly(Sarcosine) Surface Modification Imparts Stealth‐Like Properties to Liposomes
Bleher, S., J. Buck, C. Muhl, S. Sieber, S. Barnert, D. Witzigmann, J. Huwyler, M. Barz, and R. Suss
Small, 2019. 15(50): p. e1904716.
Impact Factor: 11.459
Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications
Dadfar, S.M., K. Roemhild, N.I. Drude, S. von Stillfried, R. Knuchel, F. Kiessling, and T. Lammers
Adv Drug Deliv Rev, 2019. 138: p. 302-325.
Impact Factor: 13.30
Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer–Lipid Amphiphile Conjugates of Small‐Molecule TLR7/8 Agonists
De Vrieze, J., B. Louage, K. Deswarte, Z. Zhong, R. De Coen, S. Van Herck, L. Nuhn, C. Kaas Frich, A.N. Zelikin, S. Lienenklaus, N.N. Sanders, B.N. Lambrecht, S.A. David, and B.G. De Geest
Angew Chem Int Ed Engl, 2019. 58(43): p. 15390-15395.
Impact Factor: 12.959
Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo
Ergen, C., P.M. Niemietz, F. Heymann, M. Baues, F. Gremse, R. Pola, L. van Bloois, G. Storm, F. Kiessling, C. Trautwein, T. Luedde, T. Lammers, and F. Tacke
Biomaterials, 2019. 206: p. 49-60.
Impact Factor: 10.317
High-Contrast Imaging of Nanodiamonds in Cells by Energy Filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis
Han, S., M. Raabe, L. Hodgson, J. Mantell, P. Verkade, T. Lasser, K. Landfester, T. Weil, and I. Lieberwirth
Nano Lett, 2019. 19(3): p. 2178-2185.
Impact Factor: 11.238
Prevention of Dominant IgG Adsorption on Nanocarriers in IgG‐Enriched Blood Plasma by Clusterin Precoating
Prozeller, D., J. Pereira, J. Simon, V. Mailander, S. Morsbach, and K. Landfester
Adv Sci (Weinh), 2019. 6(10): p. 1802199.
Impact Factor: 15.84
Combining Nanomedicine and Immunotherapy
Shi, Y. and T. Lammers
Acc Chem Res, 2019. 52(6): p. 1543-1554.
Impact Factor: 20.832
Investigation of charge ratio variation in mRNA – DEAE-dextran polyplex delivery systems
Siewert, C., H. Haas, T. Nawroth, A. Ziller, S.S. Nogueira, M.A. Schroer, C.E. Blanchet, D.I. Svergun, A. Radulescu, F. Bates, Y. Huesemann, M.P. Radsak, U. Sahin, and P. Langguth
Biomaterials, 2019. 192: p. 612-620.
Impact Factor: 10.317
Noncovalent Targeting of Nanocarriers to Immune Cells with Polyphosphoester‐Based Surfactants in Human Blood Plasma
Simon, J., K.N. Bauer, J. Langhanki, T. Opatz, V. Mailander, K. Landfester, and F.R. Wurm
Adv Sci (Weinh), 2019. 6(22): p. 1901199.
Impact Factor: 15.84
Nanomedicine and macroscale materials in immuno-oncology
Sun, Q., M. Barz, B.G. De Geest, M. Diken, W.E. Hennink, F. Kiessling, T. Lammers, and Y. Shi
Chem Soc Rev, 2019. 48(1): p. 351-381.
Impact Factor: 42.846
Smart cancer nanomedicine
van der Meel, R., E. Sulheim, Y. Shi, F. Kiessling, W.J.M. Mulder, and T. Lammers
Nat Nanotechnol, 2019. 14(11): p. 1007-1017.
Impact Factor: 31.538
Possibilities and Limitations of Different Separation Techniques for the Analysis of the Protein Corona
Weber, C., S. Morsbach, and K. Landfester
Angew Chem Int Ed Engl, 2019. 58(37): p. 12787-12794.
Impact Factor: 12.959
2018
Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages
Bohn, T., S. Rapp, N. Luther, M. Klein, T.J. Bruehl, N. Kojima, P. Aranda Lopez, J. Hahlbrock, S. Muth, S. Endo, S. Pektor, A. Brand, K. Renner, V. Popp, K. Gerlach, D. Vogel, C. Lueckel, D. Arnold-Schild, J. Pouyssegur, M. Kreutz, M. Huber, J. Koenig, B. Weigmann, H.C. Probst, E. von Stebut, C. Becker, H. Schild, E. Schmitt, and T. Bopp
Nat Immunol, 2018. 19(12): p. 1319-1329.
Impact Factor: 20.479
Tumor targeting via EPR: Strategies to enhance patient responses
Golombek, S.K., J.N. May, B. Theek, L. Appold, N. Drude, F. Kiessling, and T. Lammers
Adv Drug Deliv Rev, 2018. 130: p. 17-38.
Impact Factor: 13.30
Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo
Klein, P.M., S. Kern, D.J. Lee, J. Schmaus, M. Hohn, J. Gorges, U. Kazmaier, and E. Wagner
Biomaterials, 2018. 178: p. 630-642.
Impact Factor: 10.317
Protein‐Corona‐by‐Design in 2D: A Reliable Platform to Decode Bio–Nano Interactions for the Next‐Generation Quality‐by‐Design Nanomedicines
Mei, K.C., A. Ghazaryan, E.Z. Teoh, H.D. Summers, Y. Li, B. Ballesteros, J. Piasecka, A. Walters, R.C. Hider, V. Mailander, and K.T. Al-Jamal
Adv Mater, 2018: p. e1802732.
Impact Factor: 27.398
Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions
Morsbach, S., G. Gonella, V. Mailander, S. Wegner, S. Wu, T. Weidner, R. Berger, K. Koynov, D. Vollmer, N. Encinas, S.L. Kuan, T. Bereau, K. Kremer, T. Weil, M. Bonn, H.J. Butt, and K. Landfester
Angew Chem Int Ed Engl, 2018. 57(39): p. 12626-12648.
Impact Factor: 12.959
Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy
Negwer, I., A. Best, M. Schinnerer, O. Schafer, L. Capeloa, M. Wagner, M. Schmidt, V. Mailander, M. Helm, M. Barz, H.J. Butt, and K. Koynov
Nat Commun, 2018. 9(1): p. 5306.
Impact Factor: 12.121
Nanoparticle‐Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses
Nuhn, L., S. De Koker, S. Van Lint, Z. Zhong, J.P. Catani, F. Combes, K. Deswarte, Y. Li, B.N. Lambrecht, S. Lienenklaus, N.N. Sanders, S.A. David, J. Tavernier, and B.G. De Geest
Adv Mater, 2018. 30(45): p. e1803397.
Impact Factor: 27.398
FRET Monitoring of Intracellular Ketal Hydrolysis in Synthetic Nanoparticles
Nuhn, L., S. Van Herck, A. Best, K. Deswarte, M. Kokkinopoulou, I. Lieberwirth, K. Koynov, B.N. Lambrecht, and B.G. De Geest
Angew Chem Int Ed Engl, 2018. 57(33): p. 10760-10764.
Impact Factor: 12.959
Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist
Nuhn, L., L. Van Hoecke, K. Deswarte, B. Schepens, Y. Li, B.N. Lambrecht, S. De Koker, S.A. David, X. Saelens, and B.G. De Geest
Biomaterials, 2018. 178: p. 643-651.
Impact Factor: 10.317
Protein corona–mediated targeting of nanocarriers to B cells allows redirection of allergic immune responses
hen, L., S. Tenzer, W. Storck, D. Hobernik, V.K. Raker, K. Fischer, S. Decker, A. Dzionek, S. Krauthauser, M. Diken, A. Nikolaev, J. Maxeiner, P. Schuster, C. Kappel, A. Verschoor, H. Schild, S. Grabbe, and M. Bros
J Allergy Clin Immunol, 2018. 142(5): p. 1558-1570.
Impact Factor: 14.11
Hydrophilicity Regulates the Stealth Properties of Polyphosphoester‐Coated Nanocarriers
Simon, J., T. Wolf, K. Klein, K. Landfester, F.R. Wurm, and V. Mailander
Angew Chem Int Ed Engl, 2018. 57(19): p. 5548-5553.
Impact Factor: 12.959
Pre-adsorption of antibodies enables targeting of nanocarriers despite a biomolecular corona
Tonigold, M., J. Simon, D. Estupinan, M. Kokkinopoulou, J. Reinholz, U. Kintzel, A. Kaltbeitzel, P. Renz, M.P. Domogalla, K. Steinbrink, I. Lieberwirth, D. Crespy, K. Landfester, and V. Mailander
Nanotechnol, 2018. 13(9): p. 862-869.
Impact Factor: 31.538
Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles–TLR7/8 Agonist Conjugates
Van Herck, S., K. Deswarte, L. Nuhn, Z. Zhong, J.P. Portela Catani, Y. Li, N.N. Sanders, S. Lienenklaus, S. De Koker, B.N. Lambrecht, S.A. David, and B.G. De Geest
J Am Chem Soc, 2018. 140(43): p. 14300-14307.
Impact Factor: 14.612
2017
Recent advances in the use of nanoparticles for allergen-specific immunotherapy
Pohlit, H., I. Bellinghausen, H. Frey, and J. Saloga 
Allergy, 2017. 72: p. 1461-74.
Impact Factor: 6.048
more
Poly(Ethylene Glycol)Dimethacrylates with Cleavable Ketal Sites: Precursors for Cleavable PEG-Hydrogels
Pohlit, H., D. Leibig, and H. Frey 
Macromol Biosci, 2017.
Impact Factor: 3.392
more
SiRNA-mediated in vivo gene knockdown by acid-degradable cationic nanohydrogel particles
Leber, N., L. Kaps, M. Aslam, J. Schupp, A. Brose, D. Schaffel, K. Fischer, M. Diken, D. Strand, K. Koynov, A. Tuettenberg, L. Nuhn, R. Zentel, and D. Schuppan
J Control Release, 2017. 248: p. 10-23.
Impact Factor: 7.877 more
Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles
Ergen, C., F. Heymann, W. Al Rawashdeh, F. Gremse, M. Bartneck, U. Panzer, R. Pola, M. Pechar, G. Storm, N. Mohr, M. Barz, R. Zentel, F. Kiessling, C. Trautwein, T. Lammers, and F. Tacke
Biomaterials, 2017. 114: p. 106-120.
Impact Factor: 10.317 more
Immunomodulatory Therapy of Inflammatory Liver Disease Using Selectin-Binding Glycopolymers
Bartneck, M., C.T. Schlosser, M. Barz, R. Zentel, C. Trautwein, T. Lammers, and F. Tacke
ACS Nano, 2017. 11(10): p. 9689-9700.
Impact Factor: 14.588
The Influence of Block Ionomer Microstructure on Polyplex Properties: Can Simulations Help to Understand Differences in Transfection Efficiency?
Heller, P., J. Zhou, B. Weber, D. Hobernik, M. Bros, F. Schmid, and M. Barz
Small, 2017. 13(17).
Impact Factor: 11.459
Secondary‐Structure‐Driven Self‐Assembly of Reactive Polypept(o)ides: Controlling Size, Shape, and Function of Core Cross‐Linked Nanostructures
Klinker, K., O. Schafer, D. Huesmann, T. Bauer, L. Capeloa, L. Braun, N. Stergiou, M. Schinnerer, A. Dirisala, K. Miyata, K. Osada, H. Cabral, K. Kataoka, and M. Barz
Angew Chem Int Ed Engl, 2017. 56(32): p. 9608-9613.
Impact Factor: 12.959
Polymeric Selectin Ligands Mimicking Complex Carbohydrates: From Selectin Binders to Modifiers of Macrophage Migration
Moog, K.E., M. Barz, M. Bartneck, F. Beceren-Braun, N. Mohr, Z. Wu, L. Braun, J. Dernedde, E.A. Liehn, F. Tacke, T. Lammers, H. Kunz, and R. Zentel
Angew Chem Int Ed Engl, 2017. 56(5): p. 1416-1421.
Impact Factor: 12.959
Coating nanoparticles with tunable surfactants facilitates control over the protein corona
Müller, J., K.N. Bauer, D. Prozeller, J. Simon, V. Mailänder, F.R. Wurm, S. Winzen, and K. Landfester
Biomaterials, 2017. 115: p. 1-8.
Impact Factor: 10.317
Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors
Ojha, T., V. Pathak, Y. Shi, W.E. Hennink, C.T.W. Moonen, G. Storm, F. Kiessling, and T. Lammers
Adv Drug Deliv Rev, 2017. 119: p. 44-60.
Impact Factor: 13.30