Publications

Protein Corona Fingerprinting of Exocytosed Nanoparticles Reveals Time-Dependence of Exocytosis Pathways.

Oberländer J, Speth KR, Kaltbeitzel A, Lieberwirth I, Landfester K, Mailänder V. Acta Biomater. 2025 Jun 29:S1742-7061(25)00476-3. doi: 10.1016/j.actbio.2025.06.057. Online ahead of print. PMID: 40592439

Engineered protein corona sustains stealth functionality of nanocarriers in plasma

Zhang X, Si S, Lieberwirth I, Landfester K, Mailänder V. J Nanobiotechnology. 2025 Jul 14;23(1):512. doi: 10.1186/s12951-025-03565-x.

Unfolding and Degradation of Micellar Immunodrug Carriers Derived From End Group Modified Aliphatic Poly(Carbonate)s with Acid-Responsive Ketal Side Groups.

Hauck AV, Fichter M, Rosenberger LJ, Willig J, Fuchs A, Schön F, Schneider P, Medina-Montano C, Ahmad T, Erlenbusch J, Besenius P, Kaps L, Bros M, Grabbe S, Mailänder V, Groll J, Nuhn L. Adv Mater. 2026 Feb;38(8):e11752. doi: 10.1002/adma.202511752. Epub 2025 Dec 12.

Physiological pH Transition-Driven Protein Corona Dynamics Regulate Cellular Uptake and Inflammatory Responses of Silica Nanoparticles

Ge Y, Fu F, Gao Y, He T, Mailänder V, Crespy D, Landfester K, Jiang S. Adv Sci (Weinh). 2025 Nov;12(43):e02788. doi: 10.1002/advs.202502788. Epub 2025 Sep 3. PMID: 40902197; PMCID: PMC12631826.

Tuning the Functional Properties of Nanocarriers Using Tunable Nano-Biointerfaces

Alessia Pancaro, Volker Mailänder, Katharina Landfester, Anitha Ethirajan Adv Funct Mat https://doi.org/10.1002/adfm.202508121

Systematic modulation of the lipid composition enables the tuning of liposome cellular uptake.

Mateos-Maroto A, Gai M, Brückner M, da Costa Marques R, Harley I, Simon J, Mailänder V, Morsbach S, Landfester K.
Acta Biomater. 2023 Mar 1;158:463-474. doi: 10.1016/j.actbio.2022.12.058.

Interfacial Denaturation at the Droplet Simplifies the Formation of Drug-Loaded Protein Nanocapsules to Enhance Immune Response of Cells.

Chali SP, Kang J, Fichter M, Speth KR, Mailänder V, Landfester K.
Advancec Science 2024 Jul 8:e2403668. doi: 10.1002/advs.202403668.

Cellular uptake and in vivo distribution of mesenchymal-stem-cell-derived extracellular vesicles are protein corona dependent

Liam-Or R, Faruqu FN, Walters A, Han S, Xu L, Wang JT, Oberlaender J, Sanchez-Fueyo A, Lombardi G, Dazzi F, Mailaender V, Al-Jamal KT.
Nature Nanotechnology 2024 Feb 16. doi: 10.1038/s41565-023-01585-y.

Co-delivery of STING and TLR7/8 agonists in antigen-based nanocapsules to dendritic cells enhances CD8+ T cell-mediated melanoma remission.

Jenny Schunke, Natkritta Hüppe, Nicole Mangazeev, Kai R. Speth, Katja Rohde, Felicia Schön, Vanessa Bolduan, Paul Schneider, Tanja Klaus, Michael Kuske, Stephan Grabbe, Katharina Landfester , Volker Mailänder
NanoToday Volume 57, August 2024, 102365 2024

Nanobodies Outperform Antibodies - Rapid Functionalization with Equal In Vivo Targeting Properties

Jung C, Fichter M, Oberländer J, Schunke J, Bolduan V, Schneider P, Kang J, Koynov K, Mailänder V, Landfester K. Nanobodies Outperform Antibodies - Rapid Functionalization with Equal In Vivo Targeting Properties.
Advanced Materials 2024 Oct 29:e2412563. doi: 10.1002/adma.202412563.

Self-Immolative Nanobody-Cysteine Residue Modification for Controlled Immunodrug Delivery

Maximilian Scherger, Yannick A. Pilger, Judith Stickdorn, Patric Komforth, Sascha Scshmitt, Sana Arnouk, Els Lebegge, Kaloian Koynov, Hans-Joachim Räder, Jo A. Van Ginderachter, Lutz Nuhn
Advanced Therapeutics June 2023, DOI:10.1021/ acsbiomaterials.2c01106.
Impact Factor: 5

MUC1 Glycopeptide Vaccine Modified with a GalNAc Glycocluster Targets the Macrophage Galactose C-type Lectin on Dendritic Cells to Elicit an Improved Humoral Response

A. Gabba, R. Attariya, S. Behren, C. Pett, J.C. van der Horst, H. Yurugi, J. Yu, M. Urschbach, J. Sabin, G. Birrane, E. Schmitt, S.J. van Vliet, P. Besenius, U. Westerlind, P.V. Murphy, J.
Am. Chem. Soc. June 2023, DOI: 10.1021/jacs.2c12843
Impact Factor: 16.4

Efficient Self-Immolative RAFT End Group Modification for Macromolecular Immunodrug Delivery

Maximilian Scherger, Yannick A. Pilger, Judith Stickdorn, Patric Komforth, Sascha Schmitt, Kaloian Koynov, Hans-Joachim Räder, Lutz Nuhn
Biomacromolecules April 2023, 24, 2380-2391
Impact Factor: 6

Reversible Polymer–Protein Functionalization by Stepwise Introduction of Amine-Reactive, Reductive-Responsive Self-Immolative End Groups onto RAFT-Derived Polymers

Maximilian Scherger, Yannick A. Pilger, Patric Komforth, Hans-Joachim Räder, Lutz Nuhn
ACS Biomaterials Science & Engineering Jan 2023
Impact Factor: 5.4

Quality by Design (QbD) Approach for a Nanoparticulate Imiquimod Formulation as an Investigational Medicinal Product

Pielenhofer, J., S. L. Meiser, K. Gogoll, A.-M. Ciciliani, M. Denny, M. Klak, B. M. Lang, P. Staubach, S. Grabbe, H. Schild, M. P. Radsak, H. Spahn-Langguth, P. Langguth
Pharmaceutics Feb 2023;5:514. doi: 10.3390/pharmaceutics15020514
Impact Factor: 6.5

Antibacterial Nanostructured Surfaces Modulate Protein Adsorption, Inflammatory Responses, and Fibrous Capsule Formation

Visalakshan RM, Bright R, Burzava ALS, Barker AJ, Simon J, Ninan N, Palms D, Wood J, Martínez-Negro M, Morsbach S, Mailänder V, Anderson PH, Brown T, Barker D, Landfester K, Vasilev K
ACS Appl Mater Interfaces. 2023 Jan 11;15(1):220-235. doi: 10.1021/acsami.2c13415.
Impact Factor: 10.4

A new methodology combining QCM-D and proteomic profiling enables characterization of protein adsorption on 2D surfaces

Martínez-Negro M, Oberländer J, Simon J, Mailänder V, Morsbach S, Landfester K
J Colloid Interface Sci. 2023 Jan 15;630(Pt A):965-972. doi: 10.1016/j.jcis.2022.10.090.
Impact Factor: 9.9

Systematic modulation of the lipid composition enables the tuning of liposome cellular uptake

Mateos-Maroto A, Gai M, Brückner M, da Costa Marques R, Harley I, Simon J, Mailänder V, Morsbach S, Landfester K.
ACS Appl Mater Interfaces. 2023 Jan 18;15(2):2891-2900. doi: 10.1021/acsami.2c17607. Epub 2023 Jan 3.
Impact Factor: 9.2

pH-triggered Recovery of Organic Polymer Photocatalytic Particles for the Production of High Value Compounds and Enhanced Recyclability

R Li, J Heuer, T Kuckhoff, K Landfester, C Ferguson
Angew Chem Int Ed Engl. 2023 Feb 7. doi: 10.1002/anie.202217652.
Impact Factor: 16.8

Endosomal sorting results in a selective separation of the protein corona from nanoparticles

S Han, R da Costa Marques, J Simon, A Kaltbeitzel, K Koynov, Katharina Landfester, V Mailänder, I Lieberwirth
Nature Comm. volume 14, Article number: 295 (2023)
Impact Factor: 17.7

A Modular Platform of Carbohydrates-Modified Supramolecular Polymers Based on Dendritic Peptide Scaffolds

L. Li, L. Wu, M. Urschbach, D. Straßburger, X. Liu, P. Besenius, G. Chen,
ACS Polym. Au 2022, 2, 478–485. DOI: 10.1021/acspolymersau.2c00032.

Dithranol as novel co-adjuvant for non-invasive dermal vaccination

Sohl, J., A.-K. Hartmann, J. Hahlbrock, J. Bartneck, M. Stassen, M. Klein, M. Bros, S. Grabbe, F. Marini, K. Woods, B. Guezguez, M. Mack, H. Schild, S. Muth, F. Melchior, H. C. Probst, P. Langguth, M. P. Radsak
npj Vaccines 2022;7:112. doi: 10.1038/s41541-022-00530-9
Impact Factor: 9.4

Poly(ethylene glycol)-Based Surfactant Reduces the Conformational Change of Adsorbed Proteins on Nanoparticles

M. Martínez-Negro, D. Russo, S. Prévost, J. Teixeira, S. Morsbach, K. Landfester
Biomacromolecules 2022, 23, 4282–4288
Impact Factor: 7.0

PEG Spacer Length Substantially Affects Antibody-Based Nanocarrier Targeting of Dendritic Cell Subsets

M. Brückner, M. Fichter, R. da Costa Marques, K. Landfester, V. Mailänder
Pharmaceutics 2022, 14(8), 1614
Impact Factor: 6.1

Proteomics reveals differential adsorption of angiogenic platelet lysate proteins on calcium phosphate bone substitute materials

R. da Costa Marques, J. Simon, C. d’Arros, K. Landfester, K. Jurk, V. Mailänder
Regenerative Biomaterials 2022, 9, rbac044
Impact Factor: 5.2

In Situ Assembly of Platinum(II)-Metallopeptide Nanostructures Disrupts Energy Homeostasis and Cellular Metabolism

Z. Zhou, K. Maxeiner, P. Moscariello, S. Xiang, Y. Wu, Y. Ren, C.J. Whitfield, L. Xu, A. Kaltbeitzel, S. Han, D. Mücke, H. Qi, M. Wagner, U. Kaiser, K. Landfester, I. Lieberwirth, D.Y.W. Ng, T. Weil
J. Am. Chem. Soc. 2022, 144, 12219−12228
Impact Factor: 16.4

Multicomponent encapsulation into fully degradable protein nanocarriers via interfacial azide–alkyne click reaction in miniemulsion allows the co-delivery of immunotherapeutics

N. Hüppe, J. Schunke, M. Fichter, V. Mailänder, F.R. Wurm, K. Landfester
Nanoscale Horiz. 2022, 7, 908–915
Impact Factor: 11.0

Dual-Targeted Nanoreactors and Prodrugs: Hydrogen Peroxide Triggers Oxidative Damage and Prodrug Activation for Synergistic Elimination of Cancer Cells

S.-M. Jo, H.S. Kim, M. Won, C. Champanhac, J.S. Kim, F.R. Wurm, K. Landfester
Adv. Funct. Mater. 2022, 32, 2200791
Impact Factor: 19.9

Nanocarriers with Multiple Cargo Load - A Comprehensive Preparation Guideline Using Orthogonal Strategies

N. Hueppe, F.R. Wurm, K. Landfester
Macromol. Rapid Commun. 2022, 2200611
Impact Factor: 5.0

Polymer nano-systems for the encapsulation and delivery of active biomacromolecular therapeutic agents

M. Machtakova, H. Therien-Aubin, K. Landfester
Chem. Soc. Rev. 2022, 51, 128-152
Impact Factor: 60.1

Achieving dendritic cell subset-specific targeting in vivo by site-directed conjugation of targeting antibodies to nanocarriers

J. Simon, M. Fichter, G. Kuhn, M. Brückner, C. Kappel, J. Schunke, T. Klaus, S. Grabbe, K. Landfester, V. Mailänder
NanoToday 2022, 43, 101375
Impact Factor: 20.7

OVA-PEG-R848 nanocapsules stimulate neonatal conventional and plasmacytoid dendritic cells

S. Wirsching, M. Machtakova, F. Borgans, L. Pretsch, M. Fichter, M.L. Cacicedo, H. Thérien-Aubin, K. Landfester, S. Gehring
Frontiers in Pedeatrics, 2022, 10.3389/fped.2022.966113
Impact Factor: 3.4

Squaric ester-based nanogels provide no specific protein corona but behave as hydrogels that incorporate plasma proteins

Anne Huppertsberg, Christian Leps, Irina Alberg, Christine Rosenauer, Svenja Morsbach, Katharina Landfester, Stefan Tenzer, Rudolf Zentel, Lutz Nuhn – Macromolecular Rapid Communications 2022, 43, 202200318.
Impact Factor: 5.0

pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophages

Kaps L, Huppertsberg A, Choteschovsky N, Klefenz A, Durak F, Schrörs B, Diken M, Eichler E, Rosigkeit S, Schmitt S, Leps C, Schulze A, Foerster F, Bockamp E, De Geest BG, Koynov K, Räder HJ, Tenzer S, Marini F, Schuppan D, Nuhn L
Proc Natl Acad Sci U S A. 2022 Mar 22;119(12)
Impact Factor: 12.8

Systemically Administered TLR7/8 Agonist and Antigen-Conjugated Nanogels Govern Immune Responses against Tumors

Stickdorn J, Stein L, Arnold-Schild D, Hahlbrock J, Medina-Montano C, Bartneck J, Ziß T, Montermann E, Kappel C, Hobernik D, Haist M, Yurugi H, Raabe M, Best A, Rajalingam K, Radsak MP, David SA, Koynov K, Bros M, Grabbe S, Schild H, Nuhn L. ACS Nano. 2022 Mar 22;16(3)
Impact Factor: 18.0

Interfering with Host Proteases in SARS-CoV-2 Entry as a Promising Therapeutic Strategy

Müller P, Maus H, Hammerschmidt SJ, Knaff PM, Mailänder V, Schirmeister T, Kersten C. Curr Med Chem. 2022;29(4)
Impact Factor: 4.7

Temperature-Responsive Nanoparticles Enable Specific Binding of Apolipoproteins from Human Plasma

Prawatborisut M, Oberländer J, Jiang S, Graf R, Avlasevich Y, Morsbach S, Crespy D, Mailänder V, Landfester K.
Small. 2022 Jan;18(3)
Impact Factor: 15.2

Antibody-Functionalized Carnauba Wax Nanoparticles to Target Breast Cancer Cells

Iyisan B, Simon J, Avlasevich Y, Baluschev S, Mailaender V, Landfester K.
ACS Appl Bio Mater. 2022 Feb 21;5(2)
Impact Factor: 4.0

Transcriptional Heterogeneity and the Microbiome of Cutaneous T-Cell Lymphoma

Licht P, Mailänder V.
Cells. 2022 Jan 19;11(3)

Nanocarriers Made of Proteins: Intracellular Visualization of a Smart Biodegradable Drug Delivery System

Frey ML, Han S, Halim H, Kaltbeitzel A, Riedinger A, Landfester K, Lieberwirth I
Small. 2022 Apr;18(15)
Impact Factor: 15.2

Shining Light on Polymeric Drug Nanocarriers with Fluorescence Correlation Spectroscopy

Schmitt S, Nuhn L, Barz M, Butt HJ, Koynov K. Macromol Rapid Commun. 2022 Feb 17
Impact Factor: 5.0

Fluorescence Correlation Spectroscopy Monitors the Fate of Degradable Nanocarriers in the Blood Stream

Schmitt S, Huppertsberg A, Klefenz A, Kaps L, Mailänder V, Schuppan D, Butt HJ, Nuhn L, Koynov K. Fluorescence Correlation Spectroscopy Monitors the Fate of Degradable Nanocarriers in the Blood Stream. Biomacromolecules. 2022 Mar 14;23(3)
Impact Factor: 7.0

Dual Stimuli-Responsive Dynamic Covalent Peptide Tags: Toward Sequence-Controlled Release in Tumor-like Microenvironments

Zegota MM, Müller MA, Lantzberg B, Kizilsavas G, Coelho JAS, Moscariello P, Martínez-Negro M, Morsbach S, Gois PMP, Wagner M, Ng DYW, Kuan SL and Weil T

Cross-linkable Polyion Complex Micelles from Polypept(o)ide-based ABC-triblock Copolymers for siRNA Delivery

Capelôa L, Yazdi M, Zhang H, Chen X, Nie Y, Wagner E, Lächelt U and Barz M
Macromol Rapid Commun. 2021 Dec 30
Impact Factor: 5.0

Alpha-single chains of collagen type VI inhibit the fibrogenic effects of triple helical collagen VI in hepatic stellate cells

Freise C, Lee H, Chronowski C, Chan D, Cziomer J, Rühl M, Dagdelen T, Lösekann M, Erben U, Catic A, Tegge W, Schuppan D, Somasundaram R, Sahin E
PLoS One 2021 Sep 2
Impact Factor: 3.8

A structurally engineered fatty acid, icosabutate, suppresses liver inflammation and fibrosis in NASH

Fraser DA, Wang X, Lund J, Nikolić N, Iruarrizaga-Lejarreta M, Skjaeret T, Alonso C, Kastelein JJP, Rustan AC, Kim YO and Schuppan D
J Hepatol. 2021 Dec 13
Impact Factor: 30.1

pH-Dependent Behavior of Ionizable Cationic Lipids in mRNA-Carrying Lipoplexes Investigated by Molecular Dynamics Simulations

Settanni G, Brill W, Haas H and Schmid F
Macromol Rapid Commun. 2021 Dec 7
Impact Factor: 5.0

Assembly of pH-Responsive Antibody-Drug-Inspired Conjugates

Raabe M, Heck AJ, Führer S, Schauenburg D, Pieszka M, Wang T, Zegota MM, Nuhn L, Ng DYW, Kuan SL and Weil T
Macromol Biosci 2021 Nov 17
Impact Factor: 5.9

Density of Conjugated Antibody Determines the Extent of Fc Receptor Dependent Capture of Nanoparticles by Liver Sinusoidal Endothelial Cells

Kappel C, Seidl C, Medina-Montano C, Schinnerer M, Alberg I, Leps C, Sohl J, Hartmann AK, Fichter M, Kuske M, Schunke J, Kuhn G, Tubbe I, Paßlick D, Hobernik D, Bent R, Haas K, Montermann E, Walzer K, Diken M, Schmidt M, Zentel R, Nuhn L, Schild H, Tenzer S, Mailänder V, Barz M, Bros M and Grabbe S
ACS Nano 2021 Sep 28
Impact Factor: 18.0

Novel Biodegradable Composite of Calcium Phosphate Cement and the Collagen I Mimetic P-15 for Pedicle Screw Augmentation in Osteoporotic Bone

Krenzlin H, Foelger A, Mailänder V, Blase C, Brockmann M, Düber C, Ringel F and Keric N
Biomedicines 2021 Oct 4
Impact Factor: 4.8

Transparent polycarbonate coated with CeO2 nanozymes repel Pseudomonas aeruginosa PA14 biofilms

Jegel O, Pfitzner F, Gazanis A, Oberländer J, Pütz E, Lange M, von der Au M, Meermann B, Mailänder V, Klasen A, Heermann R and Tremel W
Nanoscale 2021 Dec 23
Impact Factor: 8.3

Temperature-Responsive Nanoparticles Enable Specific Binding of Apolipoproteins from Human Plasma

Prawatborisut M, Oberländer J, Jiang S, Graf R, Avlasevich Y, Morsbach S, Crespy D, Mailänder V and Landfester K
Small 2021 Nov 10
Impact Factor: 15.2

Modulating Protein Corona and Materials–Cell Interactions with Temperature‐Responsive Materials

M. Prawatborisut, S. Jiang, J. Oberländer, V. Mailänder, D. Crespy and K. Landfester
Adv. Funct. Mater 2021
Impact Factor: 19.9

Controlling the semi-permeability of protein nanocapsules influences the cellular response to macromolecular payloads

Machtakova M, Wirsching S, Gehring S, Landfester K and Thérien-Aubin H
J Mater Chem B 2021 Oct 20
Impact Factor: 7.6

Therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression

Johann K, Bohn T, Shahneh F, Luther N, Birke A, Jaurich H, Helm M, Klein M, Raker VK, Bopp T, Barz M and Becker C
Nat Commun. 2021 Oct 13;12(1):5981
Impact Factor: 17.7

RAFT Synthesis of Reactive Multifunctional Triblock-Copolymers for Polyplex Formation

N. Ritt, A. Ayaou and R. Zentel
Macromol. Chem. Phys. 2100122, online (2021); DOI: 10.1002/macp.202100122
Impact Factor: 3.0

Polymer cyclization for the emergence of hierarchical nanostructures

Chen, C., Singh, M. K.; Wunderlich, K.; Harvey, S.; Whitfield, C., Zhou, Z.; Wagner, M.; Landfester, K.; Lieberwirth, I.; Fytas, G.; Kremer, K., Mukherji, D.; Ng, D. Y. W., Weil, T.
Nature Communications 2021 doi.org/10.1038/s41467-021-24222-5
Impact Factor: 17.7

Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-Like Receptor 7/8 Agonistic Immune Modulators

A. Huppertsberg, L. Kaps, Z. Zhong, S. Schmitt, J. Stickdorn, K. Deswarte, F. Combes, C. Czysch, J. De Vrieze, S. Kasmi, N. Choteschovsky, A. Klefenz, C. Medina-Montano, P. Winterwerber, C. Chen, M. Bros, S. Lienenklaus, N. N. Sanders, K. Koynov, D. Schuppan, B. N. Lambrecht, S. David, B. G. De Geest, L. Nuhn
Journal of the American Chemical Society 2021, DOI: 10.1021/jacs.1c03772
Impact Factor: 16.4

Contactless Nanoparticle-Based Guiding of Cells by Controllable Magnetic Fields

Blümler, P.; Friedrich, R. P.; Pereira, J.; Baun, O.; Alexiou, C.; Mailänder, V
Nanotechnol Sci Appl. 2021, 14:91-100
Impact Factor: 3.8

Self-sustaining enzyme nanocapsules perform on-site chemical reactions

Machtakova, S. Han, Y. Yangazoglu, I. Lieberwirth, H. Therien-Aubin, K. Landfester
Nanoscale 2021, 13, 4051-4059
Impact Factor: 8.3

Enzyme-Loaded Nanoreactors Enable the Continuous Regeneration of Nicotinamide Adenine Dinucleotide in Artificial Metabolisms

S.M. Jo, F.R. Wurm, K. Landfester
Angew. Chem. Intern. Ed. 2021, 60, 7728-7734
Impact Factor: 16.8

Contactless Nanoparticle-Based Guiding of Cells by Controllable Magnetic Fields

Blumler, P., Friedrich, R.P., Pereira, J., Baun, O., Alexiou, C., and Mailander, V.
Nanotechnol Sci Appl, 2021. 14: p. 91-100.
Impact Factor: 6.29

The conjugation strategy affects antibody orientation and targeting properties of nanocarriers

Bruckner, M., Simon, J., Landfester, K., and Mailander, V.
Nanoscale, 2021. 13(21): p. 9816-9824.
Impact Factor: 7.79

Encapsulation of polyprodrugs enables an efficient and controlled release of dexamethasone

Li, M., Jiang, S., Haller, A., Wirsching, S., Fichter, M., Simon, J., Wagner, M., Mailander, V., Gehring, S., Crespy, D., and Landfester, K.
Nanoscale Horizons, 2021. 6(10): p. 791-800.
Impact Factor: 9.94

Brush Conformation of Polyethylene Glycol Determines the Stealth Effect of Nanocarriers in the Low Protein Adsorption Regime

Li, M., J. Simon, D. Paßlick, M.L. Frey, M. Wagner, V. Mailänder, D. Crespy, and K. Landfester
Nano Letters, 2021. 21(4): p.1591-1598.
Impact Factor: 11.238

Heparin modulates the cellular uptake of nanomedicines

Champanhac, C., H. Haas, K. Landfester, and V. Mailänder
Biomaterials Science, 2021. 9(4): p.1227-1231.
Impact Factor: 6.183

Unraveling the In Vivo Protein Corona

Simon, J., G. Kuhn, M. Fichter, S. Gehring, K. Landfester, and V. Mailander
Cells, 2021. 10(1).
Impact Factor: 4.366

An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma

Sahin, U., P. Oehm, E. Derhovanessian, R.A. Jabulowsky, M. Vormehr, M. Gold, D. Maurus, D. Schwarck-Kokarakis, A.N. Kuhn, T. Omokoko, L.M. Kranz, M. Diken, S. Kreiter, H. Haas, S. Attig, R. Rae, K. Cuk, A. Kemmer-Bruck, A. Breitkreuz, C. Tolliver, J. Caspar, J. Quinkhardt, L. Hebich, M. Stein, A. Hohberger, I. Vogler, I. Liebig, S. Renken, J. Sikorski, M. Leierer, V. Muller, H. Mitzel-Rink, M. Miederer, C. Huber, S. Grabbe, J. Utikal, A. Pinter, R. Kaufmann, J.C. Hassel, C. Loquai, and O. Tureci
Nature, 2020. 585(7823): p. 107-112.
Impact Facture: 42.778

In Vivo siRNA Delivery to Immunosuppressive Liver Macrophages by α-Mannosyl-Functionalized Cationic Nanohydrogel Particles

Kaps, L., N. Leber, A. Klefenz, N. Choteschovsky, R. Zentel, L. Nuhn, and D. Schuppan
Cells, 2020. 9(8).
Impact Factor: 4.366

Synergistic Anticancer Therapy by Ovalbumin Encapsulation‐Enabled Tandem Reactive Oxygen Species Generation

Jiang, S., M. Xiao, W. Sun, D. Crespy, V. Mailander, X. Peng, J. Fan, and K. Landfester
Angew Chem Int Ed Engl, 2020. 59(45): p. 20008-20016.
Impact Factor: 12.959

Controlling protein interactions in blood for effective liver immunosuppressive therapy by silica nanocapsules

Jiang, S., D. Prozeller, J. Pereira, J. Simon, S. Han, S. Wirsching, M. Fichter, M. Mottola, I. Lieberwirth, S. Morsbach, V. Mailander, S. Gehring, D. Crespy, and K. Landfester
Nanoscale, 2020. 12(4): p. 2626-2637.
Impact Factor: 6.895

Polymeric Nanoparticles with Neglectable Protein Corona

Alberg, I., S. Kramer, M. Schinnerer, Q. Hu, C. Seidl, C. Leps, N. Drude, D. Mockel, C. Rijcken, T. Lammers, M. Diken, M. Maskos, S. Morsbach, K. Landfester, S. Tenzer, M. Barz, and R. Zentel
Small, 2020. 16(18): p. e1907574.
Impact Factor: 11.459

Precision Anisotropic Brush Polymers by Sequence Controlled Chemistry

Chen, C., K. Wunderlich, D. Mukherji, K. Koynov, A.J. Heck, M. Raabe, M. Barz, G. Fytas, K. Kremer, D.Y.W. Ng, and T. Weil
J Am Chem Soc, 2020. 142(3): p. 1332-1340.
Impact Factor: 14.612

Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle–Cell Interactions

Dal, N.K., A. Kocere, J. Wohlmann, S. Van Herck, T.A. Bauer, J. Resseguier, S. Bagherifam, H. Hyldmo, M. Barz, B.G. De Geest, and F. Fenaroli
Small, 2020. 16(5): p. e1906719.
Impact Factor: 11.459

Integration of Indocyanine Green Analogs as Near‐Infrared Fluorescent Carrier for Precise Imaging‐Guided Gene Delivery

Liang, H., X. Chen, R. Jin, B. Ke, M. Barz, H. Ai, and Y. Nie
Small, 2020. 16(10): p. e1906538.
Impact Factor: 11.459

DNA–Polymer Nanostructures by RAFT Polymerization and Polymerization‐Induced Self‐Assembly

Luckerath, T., K. Koynov, S. Loescher, C.J. Whitfield, L. Nuhn, A. Walther, C. Barner-Kowollik, D.Y.W. Ng, and T. Weil
Angew Chem Int Ed Engl, 2020. 59(36): p. 15474-15479.
Impact Factor: 12.959

The Influence of Nanoparticle Shape on Protein Corona Formation

Madathiparambil Visalakshan, R., L.E. Gonzalez Garcia, M.R. Benzigar, A. Ghazaryan, J. Simon, A. Mierczynska-Vasilev, T.D. Michl, A. Vinu, V. Mailander, S. Morsbach, K. Landfester, and K. Vasilev
Small, 2020. 16(25): p. e2000285.
Impact Factor: 11.459

Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging

Steen, E.J.L., J.T. Jorgensen, K. Johann, K. Norregaard, B. Sohr, D. Svatunek, A. Birke, V. Shalgunov, P.E. Edem, R. Rossin, C. Seidl, F. Schmid, M.S. Robillard, J.L. Kristensen, H. Mikula, M. Barz, A. Kjaer, and M.M. Herth
ACS Nano, 2020. 14(1): p. 568-584.
Impact Factor: 14.588

Amphiphilic Polyphenylene Dendron Conjugates for Surface Remodeling of Adenovirus 5

Wagner, J., L. Li, J. Simon, L. Krutzke, K. Landfester, V. Mailander, K. Mullen, D.Y.W. Ng, Y. Wu, and T. Weil
Angew Chem Int Ed Engl, 2020. 59(14): p. 5712-5720.
Impact Factor: 12.959

Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles

Wang, B., S. Van Herck, Y. Chen, X. Bai, Z. Zhong, K. Deswarte, B.N. Lambrecht, N.N. Sanders, S. Lienenklaus, H.W. Scheeren, S.A. David, F. Kiessling, T. Lammers, B.G. De Geest, and Y. Shi
J Am Chem Soc, 2020. 142(28): p. 12133-12139.
Impact Factor: 14.612

Ligand density on nanoparticles: A parameter with critical impact on nanomedicine

Alkilany, A.M., L. Zhu, H. Weller, A. Mews, W.J. Parak, M. Barz, and N. Feliu
Adv Drug Deliv Rev, 2019. 143: p. 22-36.
Impact Factor: 13.30

Poly(Sarcosine) Surface Modification Imparts Stealth‐Like Properties to Liposomes

Bleher, S., J. Buck, C. Muhl, S. Sieber, S. Barnert, D. Witzigmann, J. Huwyler, M. Barz, and R. Suss
Small, 2019. 15(50): p. e1904716.
Impact Factor: 11.459

Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications

Dadfar, S.M., K. Roemhild, N.I. Drude, S. von Stillfried, R. Knuchel, F. Kiessling, and T. Lammers
Adv Drug Deliv Rev, 2019. 138: p. 302-325.
Impact Factor: 13.30

Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer–Lipid Amphiphile Conjugates of Small‐Molecule TLR7/8 Agonists

De Vrieze, J., B. Louage, K. Deswarte, Z. Zhong, R. De Coen, S. Van Herck, L. Nuhn, C. Kaas Frich, A.N. Zelikin, S. Lienenklaus, N.N. Sanders, B.N. Lambrecht, S.A. David, and B.G. De Geest
Angew Chem Int Ed Engl, 2019. 58(43): p. 15390-15395.
Impact Factor: 12.959

Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo

Ergen, C., P.M. Niemietz, F. Heymann, M. Baues, F. Gremse, R. Pola, L. van Bloois, G. Storm, F. Kiessling, C. Trautwein, T. Luedde, T. Lammers, and F. Tacke
Biomaterials, 2019. 206: p. 49-60.
Impact Factor: 10.317

High-Contrast Imaging of Nanodiamonds in Cells by Energy Filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis

Han, S., M. Raabe, L. Hodgson, J. Mantell, P. Verkade, T. Lasser, K. Landfester, T. Weil, and I. Lieberwirth
Nano Lett, 2019. 19(3): p. 2178-2185.
Impact Factor: 11.238

Prevention of Dominant IgG Adsorption on Nanocarriers in IgG‐Enriched Blood Plasma by Clusterin Precoating

Prozeller, D., J. Pereira, J. Simon, V. Mailander, S. Morsbach, and K. Landfester
Adv Sci (Weinh), 2019. 6(10): p. 1802199.
Impact Factor: 15.84

Combining Nanomedicine and Immunotherapy

Shi, Y. and T. Lammers
Acc Chem Res, 2019. 52(6): p. 1543-1554.
Impact Factor: 20.832

Investigation of charge ratio variation in mRNA – DEAE-dextran polyplex delivery systems

Siewert, C., H. Haas, T. Nawroth, A. Ziller, S.S. Nogueira, M.A. Schroer, C.E. Blanchet, D.I. Svergun, A. Radulescu, F. Bates, Y. Huesemann, M.P. Radsak, U. Sahin, and P. Langguth
Biomaterials, 2019. 192: p. 612-620.
Impact Factor: 10.317

Noncovalent Targeting of Nanocarriers to Immune Cells with Polyphosphoester‐Based Surfactants in Human Blood Plasma

Simon, J., K.N. Bauer, J. Langhanki, T. Opatz, V. Mailander, K. Landfester, and F.R. Wurm
Adv Sci (Weinh), 2019. 6(22): p. 1901199.
Impact Factor: 15.84

Nanomedicine and macroscale materials in immuno-oncology

Sun, Q., M. Barz, B.G. De Geest, M. Diken, W.E. Hennink, F. Kiessling, T. Lammers, and Y. Shi
Chem Soc Rev, 2019. 48(1): p. 351-381.
Impact Factor: 42.846

Smart cancer nanomedicine

van der Meel, R., E. Sulheim, Y. Shi, F. Kiessling, W.J.M. Mulder, and T. Lammers
Nat Nanotechnol, 2019. 14(11): p. 1007-1017.
Impact Factor: 31.538

Possibilities and Limitations of Different Separation Techniques for the Analysis of the Protein Corona

Weber, C., S. Morsbach, and K. Landfester
Angew Chem Int Ed Engl, 2019. 58(37): p. 12787-12794.
Impact Factor: 12.959

Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages

Bohn, T., S. Rapp, N. Luther, M. Klein, T.J. Bruehl, N. Kojima, P. Aranda Lopez, J. Hahlbrock, S. Muth, S. Endo, S. Pektor, A. Brand, K. Renner, V. Popp, K. Gerlach, D. Vogel, C. Lueckel, D. Arnold-Schild, J. Pouyssegur, M. Kreutz, M. Huber, J. Koenig, B. Weigmann, H.C. Probst, E. von Stebut, C. Becker, H. Schild, E. Schmitt, and T. Bopp
Nat Immunol, 2018. 19(12): p. 1319-1329.
Impact Factor: 20.479

Tumor targeting via EPR: Strategies to enhance patient responses

Golombek, S.K., J.N. May, B. Theek, L. Appold, N. Drude, F. Kiessling, and T. Lammers
Adv Drug Deliv Rev, 2018. 130: p. 17-38.
Impact Factor: 13.30

Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo

Klein, P.M., S. Kern, D.J. Lee, J. Schmaus, M. Hohn, J. Gorges, U. Kazmaier, and E. Wagner
Biomaterials, 2018. 178: p. 630-642.
Impact Factor: 10.317

Protein‐Corona‐by‐Design in 2D: A Reliable Platform to Decode Bio–Nano Interactions for the Next‐Generation Quality‐by‐Design Nanomedicines

Mei, K.C., A. Ghazaryan, E.Z. Teoh, H.D. Summers, Y. Li, B. Ballesteros, J. Piasecka, A. Walters, R.C. Hider, V. Mailander, and K.T. Al-Jamal
Adv Mater, 2018: p. e1802732.
Impact Factor: 27.398

Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions

Morsbach, S., G. Gonella, V. Mailander, S. Wegner, S. Wu, T. Weidner, R. Berger, K. Koynov, D. Vollmer, N. Encinas, S.L. Kuan, T. Bereau, K. Kremer, T. Weil, M. Bonn, H.J. Butt, and K. Landfester
Angew Chem Int Ed Engl, 2018. 57(39): p. 12626-12648.
Impact Factor: 12.959

Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy

Negwer, I., A. Best, M. Schinnerer, O. Schafer, L. Capeloa, M. Wagner, M. Schmidt, V. Mailander, M. Helm, M. Barz, H.J. Butt, and K. Koynov
Nat Commun, 2018. 9(1): p. 5306.
Impact Factor: 12.121

Nanoparticle‐Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses

Nuhn, L., S. De Koker, S. Van Lint, Z. Zhong, J.P. Catani, F. Combes, K. Deswarte, Y. Li, B.N. Lambrecht, S. Lienenklaus, N.N. Sanders, S.A. David, J. Tavernier, and B.G. De Geest
Adv Mater, 2018. 30(45): p. e1803397.
Impact Factor: 27.398

FRET Monitoring of Intracellular Ketal Hydrolysis in Synthetic Nanoparticles

Nuhn, L., S. Van Herck, A. Best, K. Deswarte, M. Kokkinopoulou, I. Lieberwirth, K. Koynov, B.N. Lambrecht, and B.G. De Geest
Angew Chem Int Ed Engl, 2018. 57(33): p. 10760-10764.
Impact Factor: 12.959

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

Nuhn, L., L. Van Hoecke, K. Deswarte, B. Schepens, Y. Li, B.N. Lambrecht, S. De Koker, S.A. David, X. Saelens, and B.G. De Geest
Biomaterials, 2018. 178: p. 643-651.
Impact Factor: 10.317

Protein corona–mediated targeting of nanocarriers to B cells allows redirection of allergic immune responses

hen, L., S. Tenzer, W. Storck, D. Hobernik, V.K. Raker, K. Fischer, S. Decker, A. Dzionek, S. Krauthauser, M. Diken, A. Nikolaev, J. Maxeiner, P. Schuster, C. Kappel, A. Verschoor, H. Schild, S. Grabbe, and M. Bros
J Allergy Clin Immunol, 2018. 142(5): p. 1558-1570.
Impact Factor: 14.11

Hydrophilicity Regulates the Stealth Properties of Polyphosphoester‐Coated Nanocarriers

Simon, J., T. Wolf, K. Klein, K. Landfester, F.R. Wurm, and V. Mailander
Angew Chem Int Ed Engl, 2018. 57(19): p. 5548-5553.
Impact Factor: 12.959

Pre-adsorption of antibodies enables targeting of nanocarriers despite a biomolecular corona

Tonigold, M., J. Simon, D. Estupinan, M. Kokkinopoulou, J. Reinholz, U. Kintzel, A. Kaltbeitzel, P. Renz, M.P. Domogalla, K. Steinbrink, I. Lieberwirth, D. Crespy, K. Landfester, and V. Mailander
Nanotechnol, 2018. 13(9): p. 862-869.
Impact Factor: 31.538

Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles–TLR7/8 Agonist Conjugates

Van Herck, S., K. Deswarte, L. Nuhn, Z. Zhong, J.P. Portela Catani, Y. Li, N.N. Sanders, S. Lienenklaus, S. De Koker, B.N. Lambrecht, S.A. David, and B.G. De Geest
J Am Chem Soc, 2018. 140(43): p. 14300-14307.
Impact Factor: 14.612

Recent advances in the use of nanoparticles for allergen-specific immunotherapy

Pohlit, H., I. Bellinghausen, H. Frey, and J. Saloga
Allergy, 2017. 72: p. 1461-74.
Impact Factor: 6.048

Poly(Ethylene Glycol)Dimethacrylates with Cleavable Ketal Sites: Precursors for Cleavable PEG-Hydrogels

Pohlit, H., D. Leibig, and H. Frey
Macromol Biosci, 2017.
Impact Factor: 3.392

SiRNA-mediated in vivo gene knockdown by acid-degradable cationic nanohydrogel particles

Leber, N., L. Kaps, M. Aslam, J. Schupp, A. Brose, D. Schaffel, K. Fischer, M. Diken, D. Strand, K. Koynov, A. Tuettenberg, L. Nuhn, R. Zentel, and D. Schuppan
J Control Release, 2017. 248: p. 10-23.
Impact Factor: 7.877

Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles

Ergen, C., F. Heymann, W. Al Rawashdeh, F. Gremse, M. Bartneck, U. Panzer, R. Pola, M. Pechar, G. Storm, N. Mohr, M. Barz, R. Zentel, F. Kiessling, C. Trautwein, T. Lammers, and F. Tacke
Biomaterials, 2017. 114: p. 106-120.
Impact Factor: 10.317

Immunomodulatory Therapy of Inflammatory Liver Disease Using Selectin-Binding Glycopolymers

Bartneck, M., C.T. Schlosser, M. Barz, R. Zentel, C. Trautwein, T. Lammers, and F. Tacke
ACS Nano, 2017. 11(10): p. 9689-9700.
Impact Factor: 14.588

The Influence of Block Ionomer Microstructure on Polyplex Properties: Can Simulations Help to Understand Differences in Transfection Efficiency?

Heller, P., J. Zhou, B. Weber, D. Hobernik, M. Bros, F. Schmid, and M. Barz
Small, 2017. 13(17).
Impact Factor: 11.459

Secondary‐Structure‐Driven Self‐Assembly of Reactive Polypept(o)ides: Controlling Size, Shape, and Function of Core Cross‐Linked Nanostructures

Klinker, K., O. Schafer, D. Huesmann, T. Bauer, L. Capeloa, L. Braun, N. Stergiou, M. Schinnerer, A. Dirisala, K. Miyata, K. Osada, H. Cabral, K. Kataoka, and M. Barz
Angew Chem Int Ed Engl, 2017. 56(32): p. 9608-9613.
Impact Factor: 12.959

Polymeric Selectin Ligands Mimicking Complex Carbohydrates: From Selectin Binders to Modifiers of Macrophage Migration

Moog, K.E., M. Barz, M. Bartneck, F. Beceren-Braun, N. Mohr, Z. Wu, L. Braun, J. Dernedde, E.A. Liehn, F. Tacke, T. Lammers, H. Kunz, and R. Zentel
Angew Chem Int Ed Engl, 2017. 56(5): p. 1416-1421.
Impact Factor: 12.959

Coating nanoparticles with tunable surfactants facilitates control over the protein corona

Müller, J., K.N. Bauer, D. Prozeller, J. Simon, V. Mailänder, F.R. Wurm, S. Winzen, and K. Landfester
Biomaterials, 2017. 115: p. 1-8.
Impact Factor: 10.317

Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors

Ojha, T., V. Pathak, Y. Shi, W.E. Hennink, C.T.W. Moonen, G. Storm, F. Kiessling, and T. Lammers
Adv Drug Deliv Rev, 2017. 119: p. 44-60.
Impact Factor: 13.30

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

Sahin, U., E. Derhovanessian, M. Miller, B.P. Kloke, P. Simon, M. Lower, V. Bukur, A.D. Tadmor, U. Luxemburger, B. Schrors, T. Omokoko, M. Vormehr, C. Albrecht, A. Paruzynski, A.N. Kuhn, J. Buck, S. Heesch, K.H. Schreeb, F. Muller, I. Ortseifer, I. Vogler, E. Godehardt, S. Attig, R. Rae, A. Breitkreuz, C. Tolliver, M. Suchan, G. Martic, A. Hohberger, P. Sorn, J. Diekmann, J. Ciesla, O. Waksmann, A.K. Bruck, M. Witt, M. Zillgen, A. Rothermel, B. Kasemann, D. Langer, S. Bolte, M. Diken, S. Kreiter, R. Nemecek, C. Gebhardt, S. Grabbe, C. Holler, J. Utikal, C. Huber, C. Loquai, and O. Tureci
Nature, 2017. 547(7662): p. 222-226.
Impact Factor: 42.778

Balancing Passive and Active Targeting to Different Tumor Compartments Using Riboflavin-Functionalized Polymeric Nanocarriers

Tsvetkova, Y., N. Beztsinna, M. Baues, D. Klein, A. Rix, S.K. Golombek, W. Al Rawashdeh, F. Gremse, M. Barz, K. Koynov, S. Banala, W. Lederle, T. Lammers, and F. Kiessling
Nano Lett, 2017. 17(8): p. 4665-4674.
Impact Factor: 11.238

Could allergen-specific immunotherapy benefit from the use of nanocarriers?

Pohlit, H., H. Frey, and J. Saloga
Nanomedicine, 2016. 11: p. 1329-31.
Impact Factor: 4.727

Polymerization of Ethylene Oxide, Propylene Oxide, and Other Alkylene Oxides: Synthesis, Novel
Polymer Architectures, and Bioconjugation

Herzberger, J., K. Niederer, H. Pohlit, J. Seiwert, M. Worm, F.R. Wurm, and H. Frey
Chem Rev, 2016. 116: p. 2170-243.
Impact Factor: 47.928

Vaccination with trifunctional nanoparticles that address CD8 ⁺ dendritic cells inhibits growth of established melanoma

Shen, L., S. Krauthauser, K. Fischer, D. Hobernik, Y. Abassi, A. Dzionek, A. Nikolaev, N. Voltz, M. Diken, M. Krummen, E. Montermann, I. Tubbe, S. Lorenz, D. Strand, H. Schild, S. Grabbe, and M. Bros
Nanomedicine (Lond), 2016. 11(20): p. 2647-2662.
Impact Factor: 4.727

MPLA-coated hepatitis B virus surface antigen (HBsAg) nanocapsules induce vigorous T cell responses in cord blood derived human T cells

Pietrzak-Nguyen, A., K. Piradashvili, M. Fichter, L. Pretsch, F. Zepp, F.R. Wurm, K. Landfester, and S. Gehring
Nanomedicine, 2016. 12(8): p. 2383-2394.
Impact Factor: 5.182

Design and Control of Nanoconfinement to Achieve Magnetic Resonance Contrast Agents with High Relaxivity

Malzahn, K., S. Ebert, I. Schlegel, O. Neudert, M. Wagner, G. Schutz, A. Ide, F. Roohi, K. Munnemann, D. Crespy, and K. Landfester
Advanced Healthcare Materials, 2016. 5(5): p. 567-574.
Impact Factor: 6.270

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

Kranz, L.M., M. Diken, H. Haas, S. Kreiter, C. Loquai, K.C. Reuter, M. Meng, D. Fritz, F. Vascotto, H. Hefesha, C. Grunwitz, M. Vormehr, Y. Husemann, A. Selmi, A.N. Kuhn, J. Buck, E. Derhovanessian, R. Rae, S. Attig, J. Diekmann, R.A. Jabulowsky, S. Heesch, J. Hassel, P. Langguth, S. Grabbe, C. Huber, O. Tureci, and U. Sahin
Nature, 2016. 534(7607): p. 396-401.
Impact Factor: 42.778

Polymeric hepatitis C virus non-structural protein 5A nanocapsules induce intrahepatic antigen-specific immune responses

Fichter, M., K. Piradashvili, A. Pietrzak-Nguyen, L. Pretsch, G. Kuhn, S. Strand, M. Knuf, F. Zepp, F.R. Wurm, V. Mailander, K. Landfester, and S. Gehring
Biomaterials, 2016. 108: p. 1-12.
Impact Factor: 10.317

Amphiphilic Copolymers Shuttle Drugs Across the Blood–Brain Barrier

Clemens-Hemmelmann, M., C. Kuffner, V. Metz, L. Kircher, U. Schmitt, C. Hiemke, R. Postina, and R. Zentel
Macromolecular Bioscience, 2016. 16(5): p. 655-665.
Impact Factor: 3.416

Glutathione Responsive Hyaluronic Acid Nanocapsules Obtained by Bioorthogonal Interfacial “Click” Reaction

Baier, G., M. Fichter, A. Kreyes, K. Klein, V. Mailander, S. Gehring, and K. Landfester
Biomacromolecules, 2016. 17(1): p. 148-53.
Impact Factor: 6.092

Biodegradable pH-Sensitive Poly(ethylene glycol) Nanocarriers for Allergen Encapsulation and
Controlled Release

Pohlit, H, I. Bellinghausen, M. Schömer, B. Heydenreich, J. Saloga, and H. Frey
Biomacromolecules, 2015. 16: p. 3103-11.
Impact Factor: 5.583

Biodegradable Protein Nanocontainers

Piradashvili, K., M. Fichter, K. Mohr, S. Gehring, F.R. Wurm, and K. Landfester
Biomacromolecules, 2015. 16(3): p. 815-21.
Impact Factor: 6.092

In Vivo Gene‐Silencing in Fibrotic Liver by siRNA‐Loaded Cationic Nanohydrogel Particles

Kaps, L., L. Nuhn, M. Aslam, A. Brose, F. Foerster, S. Rosigkeit, P. Renz, R. Heck, Y.O. Kim, I. Lieberwirth, D. Schuppan, and R. Zentel
Advanced Healthcare Materials, 2015. 4(18): p. 2809-2815.
Impact Factor: 6.270

Tailoring the stealth properties of biocompatible polysaccharide nanocontainers

Kang, B., P. Okwieka, S. Schottler, O. Seifert, R.E. Kontermann, K. Pfizenmaier, A. Musyanovych, R. Meyer, M. Diken, U. Sahin, V. Mailander, F.R. Wurm, and K. Landfester
Biomaterials, 2015. 49: p. 125-34.
Impact Factor: 10.317

Monophosphoryl lipid A coating of hydroxyethyl starch nanocapsules drastically increases uptake and maturation by dendritic cells while minimizing the adjuvant dosage

Fichter, M., M. Dedters, A. Pietrzak-Nguyen, L. Pretsch, C.U. Meyer, S. Strand, F. Zepp, G. Baier, K. Landfester, and S. Gehring
Vaccine, 2015. 33(7): p. 838-46.
Impact Factor: 3.143

Heparin‐Based Nanocapsules as Potential Drug Delivery Systems

Baier, G., S. Winzen, C. Messerschmidt, D. Frank, M. Fichter, S. Gehring, V. Mailander, and K. Landfester
Macromol Biosci, 2015. 15(6): p. 765-76.
Impact Factor: 3.416

Bioactive and biodegradable silica biomaterial for bone regeneration

Wang, S., X. Wang, F.G. Draenert, O. Albert, H.C. Schroder, V. Mailander, G. Mitov, and W.E. Muller
Bone, 2014. 67: p. 292-304.
Impact Factor: 4.455

Enhanced in Vivo Targeting of Murine Nonparenchymal Liver Cells with Monophosphoryl Lipid A Functionalized Microcapsules

Pietrzak-Nguyen, A., M. Fichter, M. Dedters, L. Pretsch, S.H. Gregory, C. Meyer, A. Doganci, M. Diken, K. Landfester, G. Baier, and S. Gehring
Biomacromolecules, 2014. 15(7): p. 2378-88.
Impact Factor: 6.092

A Trifunctional Dextran-Based Nanovaccine Targets and Activates Murine Dendritic Cells, and Induces Potent Cellular and Humoral Immune Responses In Vivo

Shen, L., T. Higuchi, I. Tubbe, N. Voltz, M. Krummen, S. Pektor, E. Montermann, K. Rausch, M. Schmidt, H. Schild, S. Grabbe, and M. Bros
PLoS One, 2013. 8(12): p. e80904.
Impact Factor: 2.740

Nanocapsules generated out of a polymeric dexamethasone shell suppress the inflammatory response of liver macrophages

Fichter, M., G. Baier, M. Dedters, L. Pretsch, A. Pietrzak-Nguyen, K. Landfester, and S. Gehring
Nanomedicine, 2013. 9(8): p. 1223-34.
Impact Factor: 5.182

Contrasting responses of Kupffer cells and inflammatory mononuclear phagocytes to biliary obstruction in a mouse model of cholestatic liver injury

Duwaerts, C.C., S. Gehring, C.W. Cheng, N. van Rooijen, and S.H. Gregory
Liver Int, 2013. 33(2): p. 255-65.
Impact Factor: 5.20

HPMA-LMA Copolymer Drug Carriers in Oncology: An in Vivo PET Study to Assess the Tumor Line-Specific Polymer Uptake and Body Distribution

Allmeroth, M., D. Moderegger, D. Gundel, K. Koynov, H.G. Buchholz, K. Mohr, F. Rosch, R. Zentel, and O. Thews
Biomacromolecules, 2013. 14(9): p. 3091-3101.
Impact Factor: 6.092

PEGylation of HPMA-based block copolymers enhances tumor accumulation in vivo: A quantitative study using radiolabeling and positron emission tomography

Allmeroth, M., D. Moderegger, D. Gundel, H.G. Buchholz, N. Mohr, K. Koynov, F. Rosch, O. Thews, and R. Zentel
Journal of Controlled Release, 2013. 172(1): p. 77-85.
Impact Factor: 7.877

Modifying the Body Distribution of HPMA-Based Copolymers by Molecular Weight and Aggregate Formation

Allmeroth, M., D. Moderegger, B. Biesalski, K. Koynov, F. Rosch, O. Thews, and R. Zentel
Biomacromolecules, 2011. 12(7): p. 2841-2849.
Impact Factor: 6.092

Invariant Natural Killer T Cells Suppress the Neutrophil Inflammatory Response in a Mouse Model of Cholestatic Liver Damage

Wintermeyer, P., C.W. Cheng, S. Gehring, B.L. Hoffman, M. Holub, L. Brossay, and S.H. Gregory
Gastroenterology, 2009. 136(3): p. 1048-59.
Impact Factor: 15.13

Laser capture microdissection and genetic analysis of carbon-labeled Kupffer cells

Gehring, S., E. Sabo, M.E. San Martin, E.M. Dickson, C.W. Cheng, and S.H. Gregory
World J Gastroenterol, 2009. 15(14): p. 1708-18.
Impact Factor: 3.34

Generation of Immune Responses against Hepatitis C Virus by Dendritic Cells Containing NS5 Protein-Coated Microparticles

Gehring, S., S.H. Gregory, P. Wintermeyer, C. Aloman, and J.R. Wands
Clin Vaccine Immunol, 2009. 16(2): p. 163-71.
Impact Factor: 3.01

The First Step into the Brain: Uptake of NIO‐PBCA Nanoparticles by Endothelial Cells in vitro and in vivo, and Direct Evidence for their Blood–Brain Barrier Permeation

Weiss, C.K., M.V. Kohnle, K. Landfester, T. Hauk, D. Fischer, J. Schmitz-Wienke, and V. Mailander
Chemmedchem, 2008. 3(9): p. 1395-1403.
Impact Factor: 2.80

Generation and characterization of an immunogenic dendritic cell population

Gehring, S., S.H. Gregory, P. Wintermeyer, M. San Martin, C. Aloman, and J.R. Wands
J Immunol Methods, 2008. 332(1-2): p. 18-30.
Impact Factor: 1.91

Relevant Publications

Tuning the Functional Properties of Nanocarriers Using Tunable Nano-Biointerfaces

pH-Dependent Behavior of Ionizable Cationic Lipids in mRNA-Carrying Lipoplexes Investigated by Molecular Dynamics Simulations