Relevant Publications

2021
Contactless Nanoparticle-Based Guiding of Cells by Controllable Magnetic Fields
Blumler, P., Friedrich, R.P., Pereira, J., Baun, O., Alexiou, C., and Mailander, V.
Nanotechnol Sci Appl, 2021. 14: p. 91-100.
Impact Factor: 6.29 more
The conjugation strategy affects antibody orientation and targeting properties of nanocarriers
Bruckner, M., Simon, J., Landfester, K., and Mailander, V.
Nanoscale, 2021. 13(21): p. 9816-9824.
Impact Factor: 7.79 more
Encapsulation of polyprodrugs enables an efficient and controlled release of dexamethasone
Li, M., Jiang, S., Haller, A., Wirsching, S., Fichter, M., Simon, J., Wagner, M., Mailander, V., Gehring, S., Crespy, D., and Landfester, K.
Nanoscale Horizons,  2021. 6(10): p. 791-800.
Impact Factor: 9.94 more
Brush Conformation of Polyethylene Glycol Determines the Stealth Effect of Nanocarriers in the Low Protein Adsorption Regime
Li, M., J. Simon, D. Paßlick, M.L. Frey, M. Wagner, V. Mailänder, D. Crespy, and K. Landfester
Nano Letters, 2021. 21(4): p.1591-1598.
Impact Factor: 11.238 more
Heparin modulates the cellular uptake of
nanomedicines
Champanhac, C., H. Haas, K. Landfester, and V. Mailänder
Biomaterials Science, 2021. 9(4): p.1227-1231.
Impact Factor: 6.183
more
Unraveling the In Vivo Protein Corona
Simon, J., G. Kuhn, M. Fichter, S. Gehring, K. Landfester, and V. Mailander
Cells, 2021. 10(1).
Impact Factor: 4.366 more
2020
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma
Sahin, U., P. Oehm, E. Derhovanessian, R.A. Jabulowsky, M. Vormehr, M. Gold, D. Maurus, D. Schwarck-Kokarakis, A.N. Kuhn, T. Omokoko, L.M. Kranz, M. Diken, S. Kreiter, H. Haas, S. Attig, R. Rae, K. Cuk, A. Kemmer-Bruck, A. Breitkreuz, C. Tolliver, J. Caspar, J. Quinkhardt, L. Hebich, M. Stein, A. Hohberger, I. Vogler, I. Liebig, S. Renken, J. Sikorski, M. Leierer, V. Muller, H. Mitzel-Rink, M. Miederer, C. Huber, S. Grabbe, J. Utikal, A. Pinter, R. Kaufmann, J.C. Hassel, C. Loquai, and O. Tureci
Nature, 2020. 585(7823): p. 107-112.
Impact Facture: 42.778
In Vivo siRNA Delivery to Immunosuppressive Liver Macrophages by α-Mannosyl-Functionalized Cationic Nanohydrogel Particles
Kaps, L., N. Leber, A. Klefenz, N. Choteschovsky, R. Zentel, L. Nuhn, and D. Schuppan
Cells, 2020. 9(8).
Impact Factor: 4.366 more
Synergistic Anticancer Therapy by Ovalbumin Encapsulation‐Enabled Tandem Reactive Oxygen Species Generation
Jiang, S., M. Xiao, W. Sun, D. Crespy, V. Mailander, X. Peng, J. Fan, and K. Landfester
Angew Chem Int Ed Engl, 2020. 59(45): p. 20008-20016.
Impact Factor: 12.959 more
Controlling protein interactions in blood for effective liver immunosuppressive therapy by silica nanocapsules
Jiang, S., D. Prozeller, J. Pereira, J. Simon, S. Han, S. Wirsching, M. Fichter, M. Mottola, I. Lieberwirth, S. Morsbach, V. Mailander, S. Gehring, D. Crespy, and K. Landfester
Nanoscale, 2020. 12(4): p. 2626-2637.
Impact Factor: 6.895 more
Polymeric Nanoparticles with Neglectable Protein Corona
Alberg, I., S. Kramer, M. Schinnerer, Q. Hu, C. Seidl, C. Leps, N. Drude, D. Mockel, C. Rijcken, T. Lammers, M. Diken, M. Maskos, S. Morsbach, K. Landfester, S. Tenzer, M. Barz, and R. Zentel
Small, 2020. 16(18): p. e1907574.
Impact Factor: 11.459 more
Precision Anisotropic Brush Polymers by Sequence Controlled Chemistry
Chen, C., K. Wunderlich, D. Mukherji, K. Koynov, A.J. Heck, M. Raabe, M. Barz, G. Fytas, K. Kremer, D.Y.W. Ng, and T. Weil
J Am Chem Soc, 2020. 142(3): p. 1332-1340.
Impact Factor: 14.612
Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle–Cell Interactions
Dal, N.K., A. Kocere, J. Wohlmann, S. Van Herck, T.A. Bauer, J. Resseguier, S. Bagherifam, H. Hyldmo, M. Barz, B.G. De Geest, and F. Fenaroli
Small, 2020. 16(5): p. e1906719.
Impact Factor: 11.459
Integration of Indocyanine Green Analogs as Near‐Infrared Fluorescent Carrier for Precise Imaging‐Guided Gene Delivery
Liang, H., X. Chen, R. Jin, B. Ke, M. Barz, H. Ai, and Y. Nie
Small, 2020. 16(10): p. e1906538.
Impact Factor: 11.459
DNA–Polymer Nanostructures by RAFT Polymerization and Polymerization‐Induced Self‐Assembly
Luckerath, T., K. Koynov, S. Loescher, C.J. Whitfield, L. Nuhn, A. Walther, C. Barner-Kowollik, D.Y.W. Ng, and T. Weil
Angew Chem Int Ed Engl, 2020. 59(36): p. 15474-15479.
Impact Factor: 12.959
The Influence of Nanoparticle Shape on Protein Corona Formation
Madathiparambil Visalakshan, R., L.E. Gonzalez Garcia, M.R. Benzigar, A. Ghazaryan, J. Simon, A. Mierczynska-Vasilev, T.D. Michl, A. Vinu, V. Mailander, S. Morsbach, K. Landfester, and K. Vasilev
Small, 2020. 16(25): p. e2000285.
Impact Factor: 11.459
Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging
Steen, E.J.L., J.T. Jorgensen, K. Johann, K. Norregaard, B. Sohr, D. Svatunek, A. Birke, V. Shalgunov, P.E. Edem, R. Rossin, C. Seidl, F. Schmid, M.S. Robillard, J.L. Kristensen, H. Mikula, M. Barz, A. Kjaer, and M.M. Herth
ACS Nano, 2020. 14(1): p. 568-584.
Impact Factor: 14.588
Amphiphilic Polyphenylene Dendron Conjugates for Surface Remodeling of Adenovirus 5
Wagner, J., L. Li, J. Simon, L. Krutzke, K. Landfester, V. Mailander, K. Mullen, D.Y.W. Ng, Y. Wu, and T. Weil
Angew Chem Int Ed Engl, 2020. 59(14): p. 5712-5720.
Impact Factor: 12.959
Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles
Wang, B., S. Van Herck, Y. Chen, X. Bai, Z. Zhong, K. Deswarte, B.N. Lambrecht, N.N. Sanders, S. Lienenklaus, H.W. Scheeren, S.A. David, F. Kiessling, T. Lammers, B.G. De Geest, and Y. Shi
J Am Chem Soc, 2020. 142(28): p. 12133-12139.
Impact Factor: 14.612
2019
Ligand density on nanoparticles: A parameter with critical impact on nanomedicine
Alkilany, A.M., L. Zhu, H. Weller, A. Mews, W.J. Parak, M. Barz, and N. Feliu
Adv Drug Deliv Rev, 2019. 143: p. 22-36.
Impact Factor: 13.30
Poly(Sarcosine) Surface Modification Imparts Stealth‐Like Properties to Liposomes
Bleher, S., J. Buck, C. Muhl, S. Sieber, S. Barnert, D. Witzigmann, J. Huwyler, M. Barz, and R. Suss
Small, 2019. 15(50): p. e1904716.
Impact Factor: 11.459
Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications
Dadfar, S.M., K. Roemhild, N.I. Drude, S. von Stillfried, R. Knuchel, F. Kiessling, and T. Lammers
Adv Drug Deliv Rev, 2019. 138: p. 302-325.
Impact Factor: 13.30
Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer–Lipid Amphiphile Conjugates of Small‐Molecule TLR7/8 Agonists
De Vrieze, J., B. Louage, K. Deswarte, Z. Zhong, R. De Coen, S. Van Herck, L. Nuhn, C. Kaas Frich, A.N. Zelikin, S. Lienenklaus, N.N. Sanders, B.N. Lambrecht, S.A. David, and B.G. De Geest
Angew Chem Int Ed Engl, 2019. 58(43): p. 15390-15395.
Impact Factor: 12.959
Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo
Ergen, C., P.M. Niemietz, F. Heymann, M. Baues, F. Gremse, R. Pola, L. van Bloois, G. Storm, F. Kiessling, C. Trautwein, T. Luedde, T. Lammers, and F. Tacke
Biomaterials, 2019. 206: p. 49-60.
Impact Factor: 10.317
High-Contrast Imaging of Nanodiamonds in Cells by Energy Filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis
Han, S., M. Raabe, L. Hodgson, J. Mantell, P. Verkade, T. Lasser, K. Landfester, T. Weil, and I. Lieberwirth
Nano Lett, 2019. 19(3): p. 2178-2185.
Impact Factor: 11.238
Prevention of Dominant IgG Adsorption on Nanocarriers in IgG‐Enriched Blood Plasma by Clusterin Precoating
Prozeller, D., J. Pereira, J. Simon, V. Mailander, S. Morsbach, and K. Landfester
Adv Sci (Weinh), 2019. 6(10): p. 1802199.
Impact Factor: 15.84
Combining Nanomedicine and Immunotherapy
Shi, Y. and T. Lammers
Acc Chem Res, 2019. 52(6): p. 1543-1554.
Impact Factor: 20.832
Investigation of charge ratio variation in mRNA – DEAE-dextran polyplex delivery systems
Siewert, C., H. Haas, T. Nawroth, A. Ziller, S.S. Nogueira, M.A. Schroer, C.E. Blanchet, D.I. Svergun, A. Radulescu, F. Bates, Y. Huesemann, M.P. Radsak, U. Sahin, and P. Langguth
Biomaterials, 2019. 192: p. 612-620.
Impact Factor: 10.317
Noncovalent Targeting of Nanocarriers to Immune Cells with Polyphosphoester‐Based Surfactants in Human Blood Plasma
Simon, J., K.N. Bauer, J. Langhanki, T. Opatz, V. Mailander, K. Landfester, and F.R. Wurm
Adv Sci (Weinh), 2019. 6(22): p. 1901199.
Impact Factor: 15.84
Nanomedicine and macroscale materials in immuno-oncology
Sun, Q., M. Barz, B.G. De Geest, M. Diken, W.E. Hennink, F. Kiessling, T. Lammers, and Y. Shi
Chem Soc Rev, 2019. 48(1): p. 351-381.
Impact Factor: 42.846
Smart cancer nanomedicine
van der Meel, R., E. Sulheim, Y. Shi, F. Kiessling, W.J.M. Mulder, and T. Lammers
Nat Nanotechnol, 2019. 14(11): p. 1007-1017.
Impact Factor: 31.538
Possibilities and Limitations of Different Separation Techniques for the Analysis of the Protein Corona
Weber, C., S. Morsbach, and K. Landfester
Angew Chem Int Ed Engl, 2019. 58(37): p. 12787-12794.
Impact Factor: 12.959
2018
Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages
Bohn, T., S. Rapp, N. Luther, M. Klein, T.J. Bruehl, N. Kojima, P. Aranda Lopez, J. Hahlbrock, S. Muth, S. Endo, S. Pektor, A. Brand, K. Renner, V. Popp, K. Gerlach, D. Vogel, C. Lueckel, D. Arnold-Schild, J. Pouyssegur, M. Kreutz, M. Huber, J. Koenig, B. Weigmann, H.C. Probst, E. von Stebut, C. Becker, H. Schild, E. Schmitt, and T. Bopp
Nat Immunol, 2018. 19(12): p. 1319-1329.
Impact Factor: 20.479
Tumor targeting via EPR: Strategies to enhance patient responses
Golombek, S.K., J.N. May, B. Theek, L. Appold, N. Drude, F. Kiessling, and T. Lammers
Adv Drug Deliv Rev, 2018. 130: p. 17-38.
Impact Factor: 13.30
Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo
Klein, P.M., S. Kern, D.J. Lee, J. Schmaus, M. Hohn, J. Gorges, U. Kazmaier, and E. Wagner
Biomaterials, 2018. 178: p. 630-642.
Impact Factor: 10.317
Protein‐Corona‐by‐Design in 2D: A Reliable Platform to Decode Bio–Nano Interactions for the Next‐Generation Quality‐by‐Design Nanomedicines
Mei, K.C., A. Ghazaryan, E.Z. Teoh, H.D. Summers, Y. Li, B. Ballesteros, J. Piasecka, A. Walters, R.C. Hider, V. Mailander, and K.T. Al-Jamal
Adv Mater, 2018: p. e1802732.
Impact Factor: 27.398
Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions
Morsbach, S., G. Gonella, V. Mailander, S. Wegner, S. Wu, T. Weidner, R. Berger, K. Koynov, D. Vollmer, N. Encinas, S.L. Kuan, T. Bereau, K. Kremer, T. Weil, M. Bonn, H.J. Butt, and K. Landfester
Angew Chem Int Ed Engl, 2018. 57(39): p. 12626-12648.
Impact Factor: 12.959
Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy
Negwer, I., A. Best, M. Schinnerer, O. Schafer, L. Capeloa, M. Wagner, M. Schmidt, V. Mailander, M. Helm, M. Barz, H.J. Butt, and K. Koynov
Nat Commun, 2018. 9(1): p. 5306.
Impact Factor: 12.121
Nanoparticle‐Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses
Nuhn, L., S. De Koker, S. Van Lint, Z. Zhong, J.P. Catani, F. Combes, K. Deswarte, Y. Li, B.N. Lambrecht, S. Lienenklaus, N.N. Sanders, S.A. David, J. Tavernier, and B.G. De Geest
Adv Mater, 2018. 30(45): p. e1803397.
Impact Factor: 27.398
FRET Monitoring of Intracellular Ketal Hydrolysis in Synthetic Nanoparticles
Nuhn, L., S. Van Herck, A. Best, K. Deswarte, M. Kokkinopoulou, I. Lieberwirth, K. Koynov, B.N. Lambrecht, and B.G. De Geest
Angew Chem Int Ed Engl, 2018. 57(33): p. 10760-10764.
Impact Factor: 12.959
Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist
Nuhn, L., L. Van Hoecke, K. Deswarte, B. Schepens, Y. Li, B.N. Lambrecht, S. De Koker, S.A. David, X. Saelens, and B.G. De Geest
Biomaterials, 2018. 178: p. 643-651.
Impact Factor: 10.317
Protein corona–mediated targeting of nanocarriers to B cells allows redirection of allergic immune responses
hen, L., S. Tenzer, W. Storck, D. Hobernik, V.K. Raker, K. Fischer, S. Decker, A. Dzionek, S. Krauthauser, M. Diken, A. Nikolaev, J. Maxeiner, P. Schuster, C. Kappel, A. Verschoor, H. Schild, S. Grabbe, and M. Bros
J Allergy Clin Immunol, 2018. 142(5): p. 1558-1570.
Impact Factor: 14.11
Hydrophilicity Regulates the Stealth Properties of Polyphosphoester‐Coated Nanocarriers
Simon, J., T. Wolf, K. Klein, K. Landfester, F.R. Wurm, and V. Mailander
Angew Chem Int Ed Engl, 2018. 57(19): p. 5548-5553.
Impact Factor: 12.959
Pre-adsorption of antibodies enables targeting of nanocarriers despite a biomolecular corona
Tonigold, M., J. Simon, D. Estupinan, M. Kokkinopoulou, J. Reinholz, U. Kintzel, A. Kaltbeitzel, P. Renz, M.P. Domogalla, K. Steinbrink, I. Lieberwirth, D. Crespy, K. Landfester, and V. Mailander
Nanotechnol, 2018. 13(9): p. 862-869.
Impact Factor: 31.538
Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles–TLR7/8 Agonist Conjugates
Van Herck, S., K. Deswarte, L. Nuhn, Z. Zhong, J.P. Portela Catani, Y. Li, N.N. Sanders, S. Lienenklaus, S. De Koker, B.N. Lambrecht, S.A. David, and B.G. De Geest
J Am Chem Soc, 2018. 140(43): p. 14300-14307.
Impact Factor: 14.612
2017
Recent advances in the use of nanoparticles for allergen-specific immunotherapy
Pohlit, H., I. Bellinghausen, H. Frey, and J. Saloga 
Allergy, 2017. 72: p. 1461-74.
Impact Factor: 6.048
more
Poly(Ethylene Glycol)Dimethacrylates with Cleavable Ketal Sites: Precursors for Cleavable PEG-Hydrogels
Pohlit, H., D. Leibig, and H. Frey 
Macromol Biosci, 2017.
Impact Factor: 3.392
more
SiRNA-mediated in vivo gene knockdown by acid-degradable cationic nanohydrogel particles
Leber, N., L. Kaps, M. Aslam, J. Schupp, A. Brose, D. Schaffel, K. Fischer, M. Diken, D. Strand, K. Koynov, A. Tuettenberg, L. Nuhn, R. Zentel, and D. Schuppan
J Control Release, 2017. 248: p. 10-23.
Impact Factor: 7.877 more
Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles
Ergen, C., F. Heymann, W. Al Rawashdeh, F. Gremse, M. Bartneck, U. Panzer, R. Pola, M. Pechar, G. Storm, N. Mohr, M. Barz, R. Zentel, F. Kiessling, C. Trautwein, T. Lammers, and F. Tacke
Biomaterials, 2017. 114: p. 106-120.
Impact Factor: 10.317 more
Immunomodulatory Therapy of Inflammatory Liver Disease Using Selectin-Binding Glycopolymers
Bartneck, M., C.T. Schlosser, M. Barz, R. Zentel, C. Trautwein, T. Lammers, and F. Tacke
ACS Nano, 2017. 11(10): p. 9689-9700.
Impact Factor: 14.588
The Influence of Block Ionomer Microstructure on Polyplex Properties: Can Simulations Help to Understand Differences in Transfection Efficiency?
Heller, P., J. Zhou, B. Weber, D. Hobernik, M. Bros, F. Schmid, and M. Barz
Small, 2017. 13(17).
Impact Factor: 11.459
Secondary‐Structure‐Driven Self‐Assembly of Reactive Polypept(o)ides: Controlling Size, Shape, and Function of Core Cross‐Linked Nanostructures
Klinker, K., O. Schafer, D. Huesmann, T. Bauer, L. Capeloa, L. Braun, N. Stergiou, M. Schinnerer, A. Dirisala, K. Miyata, K. Osada, H. Cabral, K. Kataoka, and M. Barz
Angew Chem Int Ed Engl, 2017. 56(32): p. 9608-9613.
Impact Factor: 12.959
Polymeric Selectin Ligands Mimicking Complex Carbohydrates: From Selectin Binders to Modifiers of Macrophage Migration
Moog, K.E., M. Barz, M. Bartneck, F. Beceren-Braun, N. Mohr, Z. Wu, L. Braun, J. Dernedde, E.A. Liehn, F. Tacke, T. Lammers, H. Kunz, and R. Zentel
Angew Chem Int Ed Engl, 2017. 56(5): p. 1416-1421.
Impact Factor: 12.959
Coating nanoparticles with tunable surfactants facilitates control over the protein corona
Müller, J., K.N. Bauer, D. Prozeller, J. Simon, V. Mailänder, F.R. Wurm, S. Winzen, and K. Landfester
Biomaterials, 2017. 115: p. 1-8.
Impact Factor: 10.317
Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors
Ojha, T., V. Pathak, Y. Shi, W.E. Hennink, C.T.W. Moonen, G. Storm, F. Kiessling, and T. Lammers
Adv Drug Deliv Rev, 2017. 119: p. 44-60.
Impact Factor: 13.30
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
Sahin, U., E. Derhovanessian, M. Miller, B.P. Kloke, P. Simon, M. Lower, V. Bukur, A.D. Tadmor, U. Luxemburger, B. Schrors, T. Omokoko, M. Vormehr, C. Albrecht, A. Paruzynski, A.N. Kuhn, J. Buck, S. Heesch, K.H. Schreeb, F. Muller, I. Ortseifer, I. Vogler, E. Godehardt, S. Attig, R. Rae, A. Breitkreuz, C. Tolliver, M. Suchan, G. Martic, A. Hohberger, P. Sorn, J. Diekmann, J. Ciesla, O. Waksmann, A.K. Bruck, M. Witt, M. Zillgen, A. Rothermel, B. Kasemann, D. Langer, S. Bolte, M. Diken, S. Kreiter, R. Nemecek, C. Gebhardt, S. Grabbe, C. Holler, J. Utikal, C. Huber, C. Loquai, and O. Tureci
Nature, 2017. 547(7662): p. 222-226.
Impact Factor: 42.778
Balancing Passive and Active Targeting to Different Tumor Compartments Using Riboflavin-Functionalized Polymeric Nanocarriers
Tsvetkova, Y., N. Beztsinna, M. Baues, D. Klein, A. Rix, S.K. Golombek, W. Al Rawashdeh, F. Gremse, M. Barz, K. Koynov, S. Banala, W. Lederle, T. Lammers, and F. Kiessling
Nano Lett, 2017. 17(8): p. 4665-4674.
Impact Factor: 11.238
2016
Pohlit, H., H. Frey, and J. Saloga
Nanomedicine, 2016. 11: p. 1329-31.
Impact Factor: 4.727
more
Polymerization of Ethylene Oxide, Propylene Oxide, and Other Alkylene Oxides: Synthesis, NovelPolymer Architectures, and Bioconjugation
Herzberger, J., K.  Niederer, H. Pohlit, J. Seiwert, M. Worm, F.R. Wurm, and H. Frey
Chem Rev, 2016. 116: p. 2170-243.
Impact Factor: 47.928
more
Vaccination with trifunctional nanoparticles that address CD8 + dendritic cells inhibits growth of established melanoma
Shen, L., S. Krauthauser, K. Fischer, D. Hobernik, Y. Abassi, A. Dzionek, A. Nikolaev, N. Voltz, M. Diken, M. Krummen, E. Montermann, I. Tubbe, S. Lorenz, D. Strand, H. Schild, S. Grabbe, and M. Bros
Nanomedicine (Lond), 2016. 11(20): p. 2647-2662.
Impact Factor: 4.727 more
MPLA-coated hepatitis B virus surface antigen (HBsAg) nanocapsules induce vigorous T cell responses in cord blood derived human T cells
Pietrzak-Nguyen, A., K. Piradashvili, M. Fichter, L. Pretsch, F. Zepp, F.R. Wurm, K. Landfester, and S. Gehring
Nanomedicine, 2016. 12(8): p. 2383-2394.
Impact Factor: 5.182 more
Design and Control of Nanoconfinement to Achieve Magnetic Resonance Contrast Agents with High Relaxivity
Malzahn, K., S. Ebert, I. Schlegel, O. Neudert, M. Wagner, G. Schutz, A. Ide, F. Roohi, K. Munnemann, D. Crespy, and K. Landfester
Advanced Healthcare Materials, 2016. 5(5): p. 567-574.
Impact Factor: 6.270 more
Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
Kranz, L.M., M. Diken, H. Haas, S. Kreiter, C. Loquai, K.C. Reuter, M. Meng, D. Fritz, F. Vascotto, H. Hefesha, C. Grunwitz, M. Vormehr, Y. Husemann, A. Selmi, A.N. Kuhn, J. Buck, E. Derhovanessian, R. Rae, S. Attig, J. Diekmann, R.A. Jabulowsky, S. Heesch, J. Hassel, P. Langguth, S. Grabbe, C. Huber, O. Tureci, and U. Sahin
Nature, 2016. 534(7607): p. 396-401.
Impact Factor: 42.778 more
Polymeric hepatitis C virus non-structural protein 5A nanocapsules induce intrahepatic antigen-specific immune responses
Fichter, M., K. Piradashvili, A. Pietrzak-Nguyen, L. Pretsch, G. Kuhn, S. Strand, M. Knuf, F. Zepp, F.R. Wurm, V. Mailander, K. Landfester, and S. Gehring
Biomaterials, 2016. 108: p. 1-12.
Impact Factor: 10.317 more
Amphiphilic Copolymers Shuttle Drugs Across the Blood–Brain Barrier
Clemens-Hemmelmann, M., C. Kuffner, V. Metz, L. Kircher, U. Schmitt, C. Hiemke, R. Postina, and R. Zentel
Macromolecular Bioscience, 2016. 16(5): p. 655-665.
Impact Factor: 3.416 more
Glutathione Responsive Hyaluronic Acid Nanocapsules Obtained by Bioorthogonal Interfacial “Click” Reaction
Baier, G., M. Fichter, A. Kreyes, K. Klein, V. Mailander, S. Gehring, and K. Landfester
Biomacromolecules, 2016. 17(1): p. 148-53.
Impact Factor: 6.092 more
2015
Biodegradable pH-Sensitive Poly(ethylene glycol) Nanocarriers for Allergen Encapsulation andControlled Release
Pohlit, H, I. Bellinghausen, M. Schömer, B. Heydenreich, J. Saloga, and H. Frey
Biomacromolecules, 2015. 16: p. 3103-11.
Impact Factor: 5.583
more
Biodegradable Protein Nanocontainers
Piradashvili, K., M. Fichter, K. Mohr, S. Gehring, F.R. Wurm, and K. Landfester
Biomacromolecules, 2015. 16(3): p. 815-21.
Impact Factor: 6.092 more
In Vivo Gene‐Silencing in Fibrotic Liver by siRNA‐Loaded Cationic Nanohydrogel Particles
Kaps, L., L. Nuhn, M. Aslam, A. Brose, F. Foerster, S. Rosigkeit, P. Renz, R. Heck, Y.O. Kim, I. Lieberwirth, D. Schuppan, and R. Zentel
Advanced Healthcare Materials, 2015. 4(18): p. 2809-2815.
Impact Factor: 6.270 more
Tailoring the stealth properties of biocompatible polysaccharide nanocontainers
Kang, B., P. Okwieka, S. Schottler, O. Seifert, R.E. Kontermann, K. Pfizenmaier, A. Musyanovych, R. Meyer, M. Diken, U. Sahin, V. Mailander, F.R. Wurm, and K. Landfester
Biomaterials, 2015. 49: p. 125-34.
Impact Factor: 10.317 more
Monophosphoryl lipid A coating of hydroxyethyl starch nanocapsules drastically increases uptake and maturation by dendritic cells while minimizing the adjuvant dosage
Fichter, M., M. Dedters, A. Pietrzak-Nguyen, L. Pretsch, C.U. Meyer, S. Strand, F. Zepp, G. Baier, K. Landfester, and S. Gehring
Vaccine, 2015. 33(7): p. 838-46.
Impact Factor: 3.143 more
Heparin‐Based Nanocapsules as Potential Drug Delivery Systems
Baier, G., S. Winzen, C. Messerschmidt, D. Frank, M. Fichter, S. Gehring, V. Mailander, and K. Landfester
Macromol Biosci, 2015. 15(6): p. 765-76.
Impact Factor: 3.416 more
2014
Bioactive and biodegradable silica biomaterial for bone regeneration
Wang, S., X. Wang, F.G. Draenert, O. Albert, H.C. Schroder, V. Mailander, G. Mitov, and W.E. Muller
Bone, 2014. 67: p. 292-304.
Impact Factor: 4.455 more
Enhanced in Vivo Targeting of Murine Nonparenchymal Liver Cells with Monophosphoryl Lipid A Functionalized Microcapsules
Pietrzak-Nguyen, A., M. Fichter, M. Dedters, L. Pretsch, S.H. Gregory, C. Meyer, A. Doganci, M. Diken, K. Landfester, G. Baier, and S. Gehring
Biomacromolecules, 2014. 15(7): p. 2378-88.
Impact Factor: 6.092 more
2013
A Trifunctional Dextran-Based Nanovaccine Targets and Activates Murine Dendritic Cells, and Induces Potent Cellular and Humoral Immune Responses In Vivo
Shen, L., T. Higuchi, I. Tubbe, N. Voltz, M. Krummen, S. Pektor, E. Montermann, K. Rausch, M. Schmidt, H. Schild, S. Grabbe, and M. Bros
PLoS One, 2013. 8(12): p. e80904.
Impact Factor: 2.740 more
Nanocapsules generated out of a polymeric dexamethasone shell suppress the inflammatory response of liver macrophages
Fichter, M., G. Baier, M. Dedters, L. Pretsch, A. Pietrzak-Nguyen, K. Landfester, and S. Gehring
Nanomedicine, 2013. 9(8): p. 1223-34.
Impact Factor: 5.182 more
Contrasting responses of Kupffer cells and inflammatory mononuclear phagocytes to biliary obstruction in a mouse model of cholestatic liver injury
Duwaerts, C.C., S. Gehring, C.W. Cheng, N. van Rooijen, and S.H. Gregory
Liver Int, 2013. 33(2): p. 255-65.
Impact Factor: 5.20 more
HPMA-LMA Copolymer Drug Carriers in Oncology: An in Vivo PET Study to Assess the Tumor Line-Specific Polymer Uptake and Body Distribution
Allmeroth, M., D. Moderegger, D. Gundel, K. Koynov, H.G. Buchholz, K. Mohr, F. Rosch, R. Zentel, and O. Thews
Biomacromolecules, 2013. 14(9): p. 3091-3101.
Impact Factor: 6.092 more
PEGylation of HPMA-based block copolymers enhances tumor accumulation in vivo: A quantitative study using radiolabeling and positron emission tomography
Allmeroth, M., D. Moderegger, D. Gundel, H.G. Buchholz, N. Mohr, K. Koynov, F. Rosch, O. Thews, and R. Zentel
Journal of Controlled Release, 2013. 172(1): p. 77-85.
Impact Factor: 7.877 more
2011
Modifying the Body Distribution of HPMA-Based Copolymers by Molecular Weight and Aggregate Formation
Allmeroth, M., D. Moderegger, B. Biesalski, K. Koynov, F. Rosch, O. Thews, and R. Zentel
Biomacromolecules, 2011. 12(7): p. 2841-2849.
Impact Factor: 6.092 more
2009
Invariant Natural Killer T Cells Suppress the Neutrophil Inflammatory Response in a Mouse Model of Cholestatic Liver Damage
Wintermeyer, P., C.W. Cheng, S. Gehring, B.L. Hoffman, M. Holub, L. Brossay, and S.H. Gregory
Gastroenterology, 2009. 136(3): p. 1048-59.
Impact Factor: 15.13 more
Laser capture microdissection and genetic analysis of carbon-labeled Kupffer cells
Gehring, S., E. Sabo, M.E. San Martin, E.M. Dickson, C.W. Cheng, and S.H. Gregory
World J Gastroenterol, 2009. 15(14): p. 1708-18.
Impact Factor: 3.34 more
Generation of Immune Responses against Hepatitis C Virus by Dendritic Cells Containing NS5 Protein-Coated Microparticles
Gehring, S., S.H. Gregory, P. Wintermeyer, C. Aloman, and J.R. Wands
Clin Vaccine Immunol, 2009. 16(2): p. 163-71.
Impact Factor: 3.01 more
2008